Automated CAR-T cell therapy for relapsed large B-cell lymphoma
Part of Cancer clinical trials.
This early-stage trial tests an automated version of axicabtagene ciloleucel (a CAR-T cell therapy) for large B-cell lymphoma that has come back or stopped responding to initial chemotherapy. CAR-T therapy uses your own immune cells, modified in a lab to fight cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Diagnosis of large B-cell lymphoma that has relapsed (returned) or become refractory (stopped responding to) first-line chemotherapy
- At least one measurable tumor on imaging
- No lymphoma in the brain or spinal fluid
- Adequate organ function (bone marrow, kidneys, liver, lungs, heart)
- At least 2 weeks since your last cancer treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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