Clin2
NCT07608159Possibly a fitNot yet recruiting

Combination treatment before surgery for stage II-III lung cancer

Non Small Cell Lung CancerStereotactic Body RadiotherapyNeoadjuvant ChemoimmunotherapySurgery

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new combination of radiation, immunotherapy, and chemotherapy given before surgery for stage II or III lung cancer. The goal is to see if this approach can shrink tumors and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
201 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Be between 18 and 75 years old
  • Have stage II or III lung cancer that can be removed with surgery
  • Have not had prior treatment for lung cancer
  • Have good overall health and ability to perform daily tasks
  • Your tumor must not have certain gene changes (EGFR or ALK)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06718309Recruiting· Phase 2
Chemo and immunotherapy with targeted radiation before surgery for lung cancer

This trial tests giving chemotherapy, immunotherapy, and targeted radiation before surgery for people with non-small cell lung cancer that can be removed. The goal is to see if this combination shrinks tumors and improves outcomes.

Hangzhou, Zhejiang
NCT07845916Not yet recruiting· Phase 2
Pre-surgery combination therapy for stage II-III lung cancer

This trial tests a combination of radiation, an immunotherapy drug called tislelizumab, and chemotherapy given before surgery for non-small cell lung cancer that has not spread too far (stage II-III). The goal is to see if this approach can shrink tumors and improve outcomes.

Wuhan, Hubei
NCT06800339Recruiting· Phase 1
Immunotherapy and radiation before surgery for lung cancer

This trial tests combining chemotherapy, immunotherapy, and a low dose of radiation before surgery for people with non-small cell lung cancer that is borderline resectable (can potentially be removed but is close to nearby structures). It aims to see if this approach can shrink the tumor enough to allow successful surgery.

Baltimore, Maryland
NCT04933903Recruiting· Phase 2
Neoadjuvant low-dose radiation plus immunotherapy before lung surgery

This trial tests whether giving low-dose focused radiation and two immunotherapy drugs before lung surgery can improve outcomes for people with operable, resectable non-small cell lung cancer. It aims to shrink or control the cancer before surgery and help reduce the chance it comes back.

Providence, Rhode Island
NCT06877299Recruiting· Phase 2
Combination Therapy for Stage IIA-IIIB Lung Cancer

This trial tests a combination of low-dose radiation, focused high-dose radiation (SBRT), chemotherapy, and an immunotherapy drug (tislelizumab) for people with stage IIA to IIIB non-small cell lung cancer that hasn't been treated yet. The goal is to see if this approach can help shrink tumors and improve outcomes before or instead of surgery.

Chengdu, China
NCT06467617Recruiting· Phase 2
Immunotherapy and chemo before and after lung cancer surgery

This trial tests a combination of an immunotherapy drug (adebrelimab) plus chemotherapy and another drug (recaticimab) before and after surgery for people with stage II or III lung cancer that can be removed. The goal is to see if this approach helps shrink tumors and improves outcomes.

Beijing, Beijing Municipality

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.