Clin2
NCT07609485Likely a fitRecruiting

Understanding Why CAR-T Cell Therapy Works or Fails

CancerHematologic Malignancy

Part of Blood & lymphatic, Cancer clinical trials.

This study collects blood and tissue samples from adults receiving CAR-T cell therapy (an advanced cancer treatment) to understand why it works well for some patients but not others. The goal is to find biological markers that predict treatment success.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
700 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years old or older
  • You are able and willing to provide informed consent
  • You are receiving a commercially approved CAR-T therapy (not an experimental one)
  • You have medical insurance or healthcare coverage
  • You are not participating in another study that restricts your privacy rights

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05887167Recruiting· Phase 1
Test safety of making CAR T cells from your own blood

This Phase 1 study looks at whether it is safe and practical to collect your own stem cells and use them to support CAR T-cell therapy for certain blood cancers that have come back or did not respond. It aims to find the best way to combine these steps, which may help some people receive CAR T treatment.

Los Angeles, California
NCT05807789Recruiting
Genetic testing during CAR-T treatment for adults

This study looks at a patient’s genetic (molecular) information while they receive CAR-T cell therapy. The goal is to better understand how different biological factors may affect CAR-T treatment.

Bologna, Italy
NCT04209829Not yet recruiting
CAR-T cell therapy for blood cancers based on tumor traits

This study looks at how well CAR-T cell therapy—a treatment that uses your own immune cells to fight cancer—works for people with certain blood cancers like lymphoma, acute lymphoblastic leukemia, or multiple myeloma. The goal is to see if the characteristics of the tumor affect how well the treatment works.

NCT04892433Recruiting
Tissue study for people getting CAR-T cell therapy

This study looks at tissue samples from adults who are receiving CAR-T cell therapy for blood-related conditions. It aims to learn more about how CAR-T works and what changes happen in the body, which may help improve future care.

Bologna, Italy
NCT07108868Recruiting· Phase 1
Study of MB-CART2219.1 for blood cancers

This trial tests a new CAR T-cell therapy called MB-CART2219.1 in people with certain types of blood cancer (like lymphoma or leukemia) that have come back or not responded to other treatments. CAR T-cells are your own immune cells that are modified to better find and kill cancer cells.

Tübingen, Baden-Wurttemberg
NCT06607289Recruiting
Blood cancer patients on CAR-T therapy long-term study

This study is for people with blood cancers who are treated with CAR-T cell therapy. Researchers will follow participants over time to learn more about how this therapy works in the real world.

Tianjin, Tianjin Municipality

Hear when a new Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.