Amnioinfusion for chorioamnionitis: protecting newborn brain health
Part of Genetic & congenital, Women’s health & pregnancy clinical trials.
This study tests whether a treatment during labor called amnioinfusion (putting sterile fluid into the uterus) can help lower the risk of brain injury in babies when the mother has chorioamnionitis, an infection of the amniotic sac. The goal is to see if this simple procedure improves newborn outcomes and reduces the chances of long-term developmental problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old
- You must be carrying a single baby (not twins or more)
- Your baby is full term or close to it (at least 36 weeks along)
- You are in labor
- You have a diagnosis of chorioamnionitis (infection in the womb) based on fever and at least one other sign, like high white blood cell count, cloudy or smelly discharge, or a fast baby heartbeat
- Your cervix is dilated enough to allow placement of a small catheter for the procedure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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