Preventing bleeding in the brain of very premature babies
Treatments studied
Part of Brain & nervous system clinical trials.
This study tests if giving a single dose of a medicine called indomethacin to very premature babies can help prevent bleeding in the brain. The medicine is given soon after birth to babies born before 26 weeks of pregnancy or weighing less than 750 grams.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is born before 26 weeks of pregnancy, or weighs less than 750 grams at birth
- Your baby does not have a heart condition that depends on a special blood vessel to survive
- Your baby does not have severe breathing problems that need extra oxygen for more than 2 hours
- Your baby has not had inhaled nitric oxide treatment for high blood pressure in the lungs
- Your baby has not received hydrocortisone (a steroid) before or after birth
- Your baby has no known kidney problems and has a normal blood platelet count
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at ways to prevent, find early, and manage bleeding in the brain and the fluid buildup that can follow in premature babies. If your baby had such bleeding and fluid buildup, the study may offer close monitoring and care to help improve outcomes.
This study looks at premature babies who are born very early and weigh very little, to understand bleeding in the brain (called intraventricular hemorrhage). If your baby is eligible, the research may help doctors learn more about this condition and how to manage it.
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