Clin2
NCT07612020Likely a fitRecruiting

How Well a New Injection Works Compared to IV

Healthy Volunteers

Treatments studied

This study tests a new medicine called empasiprubart that can be injected under the skin using an autoinjector (like an EpiPen). Researchers want to see how much of the medicine gets into your bloodstream and whether the injection works as well as an IV infusion. You'll be a healthy volunteer helping them understand if this new delivery method is effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
130 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 65 years old
  • You weigh between 110 and 264 pounds (50–120 kg)
  • Your body mass index (BMI) is between 18 and 35
  • You are in good general health with no serious medical or mental health conditions
  • You have not been diagnosed with lupus (SLE) and certain lupus blood tests must be negative
  • You have never received empasiprubart in a previous clinical trial

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07782775Recruiting· Phase 1
Comparing two ways to give efgartigimod in healthy volunteers

This study compares two methods of giving the drug efgartigimod under the skin in healthy adults. It helps ensure both methods work the same way, which may make treatment easier for patients in the future.

Montreal
NCT07673601Recruiting· Phase 1
Study of adimanebart in healthy adults

This study tests how a single injection of adimanebart is absorbed by the body and how it travels through the bloodstream. It is for healthy adults to help understand the drug's behavior.

Montreal
NCT07091630Recruiting· Phase 3
A study of empasiprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)

This study tests a new medicine called Empasiprubart for adults with ongoing CIDP. It aims to see if fewer symptoms return and if it can replace current treatments.

Birmingham, Alabama
NCT06920004Recruiting· Phase 3
Testing empasiprubart vs IVIg for chronic CIDP

This study tests an investigational drug called empasiprubart against standard IVIg in adults with CIDP. The goal is to see if it is safer and more effective for people who still have symptoms despite IVIg therapy.

Birmingham, Alabama
NCT07638566Not yet recruiting· Phase 2/Phase 3
Empasiprubart for Teenage CIDP: Dose and Safety Study

This trial tests a new medicine called empasiprubart in teenagers ages 12–17 with CIDP, a rare nerve disease that causes weakness and numbness. Researchers want to find the right dose and see if it safely reduces symptoms.

NCT07673627Recruiting· Phase 2
Testing empasiprubart for generalized myasthenia gravis

This trial tests a new drug called empasiprubart for people with generalized myasthenia gravis (gMG) who have a certain antibody (AChR-Ab). It is given as a monthly IV infusion (into a vein) and aims to improve muscle weakness and daily functioning.

Miami, Florida

Hear when a new Healthy Volunteers trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.