Aminophylline to help remove kidney stones in children
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether a medication called aminophylline, placed directly in the bladder during surgery, helps doctors access and remove small stones stuck in the lower ureter (the tube that carries urine from the kidney). It's designed for children whose ureter is difficult to reach during the initial procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is between 2 and 18 years old
- Your child has one kidney stone in the lower ureter, confirmed by CT scan, measuring 5–15 mm (about the size of a small pea to a peppercorn)
- Your child needs ureteroscopy surgery (a camera-based procedure to remove the stone)
- Your child's urine is free of infection before surgery (or was treated if previously infected)
- Your child's doctor was unable to gently access the ureter during an initial attempt, triggering enrollment in this trial
- Your child has no allergy to aminophylline, theophylline, or ethylenediamine, and hasn't taken these drugs in the past 24 hours
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether injecting aminophylline (a medication that relaxes muscles) into the bladder can help doctors place a stent (small tube) to relieve a blocked ureter caused by a kidney stone. The goal is to improve kidney function when one kidney is blocked and not working.
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This trial compares two types of ureteral stents (small tubes that help urine drain from the kidney to the bladder) in children having surgery for kidney stones. The goal is to see which type causes fewer symptoms like pain or discomfort.
This trial tests if placing aminophylline into the ureter during a stone removal procedure (flexible ureteroscopy) reduces complications. It may help people with kidney stones smaller than 2 cm who have not had a ureteral stent placed before.
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