Light therapy to treat melanoma side effects in the gut and liver
Treatments studied
Part of Cancer, Digestive system, Skin clinical trials.
This trial tests extracorporeal photopheresis (ECP)—a treatment that removes blood, treats it with light, and returns it to your body—to help control severe gut and liver inflammation caused by melanoma immunotherapy drugs that weren't helped by steroids. The goal is to let you continue or restart cancer treatment safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Advanced melanoma (stage III or IV) that spread or cannot be removed by surgery
- You received immunotherapy drugs (checkpoint inhibitors) that were paused or stopped because of severe gut inflammation and/or liver inflammation
- Your gut inflammation or liver inflammation is grade 2 or worse and did not improve enough with steroid treatment
- You have evidence of gut inflammation confirmed by endoscopy (a camera test looking inside your digestive tract)
- You are well enough to tolerate the ECP procedure and its effects on fluid balance
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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