Suzetrigine to Reduce Pain and Opioid Use After Knee Surgery
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether a new pain medication called suzetrigine, when combined with other pain-management strategies, can reduce pain and the need for opioids after total knee replacement surgery. The goal is to help patients recover comfortably while using fewer opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a total knee replacement surgery for osteoarthritis (wear-and-tear of the knee joint)
- You are between 18 and 95 years old
- You have not been taking opioids daily in the 4 weeks before your surgery
- You do not have serious heart, kidney, or liver problems
- You are able to take NSAIDs (over-the-counter pain relievers like ibuprofen) without problems
- You do not have uncontrolled diabetes, active stomach ulcers, or severe infections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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