Targeted Brain Stimulation for Parkinson's Motor and Non-Motor Symptoms
Part of Brain & nervous system clinical trials.
This trial tests a non-invasive brain stimulation technique (using electrical currents applied through the scalp) aimed at the subthalamic nucleus—a brain region involved in movement control—to help reduce both movement-related symptoms (like tremor and stiffness) and non-movement symptoms (like mood and sleep problems) in people with Parkinson's disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old
- You have been diagnosed with Parkinson's disease (either clinically established or clinically probable) according to standard diagnostic criteria
- Your Parkinson's disease is at Hoehn-Yahr stage 2 or higher (meaning symptoms affect both sides of your body or you have balance problems)
- You have been on stable Parkinson's medications for at least 4 weeks and are willing to keep them stable during the study
- You do not have metal implants (like pacemakers or cochlear implants) that would make brain stimulation unsafe
- You are able to undergo MRI scans and do not have conditions that make MRI unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
This trial tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (TTIS) that you can use at home with remote supervision. It aims to improve movement problems like stiffness, tremor, and slowness in people with mild-to-moderate Parkinson's disease.
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
This trial tests a non-invasive brain stimulation technique, called temporal interference stimulation, that aims to improve movement and non-movement symptoms in people with Parkinson's disease. If you have had Parkinson's for at least a year and are on stable medication, you might qualify.
This trial tests a new, non-invasive brain stimulation technique (called temporal interference stimulation) to see if it can improve Parkinson's symptoms. It uses MRI to guide the treatment, and the goal is to help with movement and other symptoms without surgery.
This trial tests a new type of brain stimulation (called temporal interference stimulation) targeted at specific brain regions to help improve Parkinson's disease symptoms. Researchers will use MRI imaging and behavioral assessments to see if this approach can reduce movement problems and improve quality of life.
Hear when a new Parkinson's Disease (PD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.