Medication to reduce tearing during childbirth
Part of Injuries & trauma, Women’s health & pregnancy clinical trials.
This study tests whether a medicine called papaverine, given during labor, can help prevent tears in the perineum (the area between the vagina and anus) during childbirth. It may make delivery easier and reduce the need for stitches.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having your first baby.
- You are 18 years or older.
- You are pregnant with one baby (not twins or more).
- Your pregnancy is full-term (37 to 42 weeks).
- Your baby is positioned head-down.
- You are in labor and your cervix is at least 2 cm dilated.
- You do not have certain heart or liver conditions, or an allergy to papaverine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a treatment made from your own blood (platelet-rich plasma) to see if it reduces pain after childbirth when you had a perineal tear or a cut (episiotomy). If it works, it could help you recover more comfortably.
This study tests whether a medicine called papaverine can shorten the pushing phase of labor in women whose labor is started with a balloon catheter. If you are planning a vaginal delivery and meet the other criteria, you may be able to join.
This study tests whether an IV medication called papaverine can help induce labor in pregnant people at term (37+ weeks) whose water has broken but labor hasn't started yet. The goal is to see if this medication makes labor start naturally and reduces the need for cesarean delivery.
This study tests whether giving papaverine through a vein can help start labour in women whose water has broken but who are not yet having contractions. Papaverine is a medicine that relaxes smooth muscles, which may help the cervix prepare for delivery.
This study tests whether a gentle massage of the area between the vagina and anus during labor can help reduce tears or the need for cuts during childbirth. It may be a good option if you are in labor and want to lower your risk of perineal injury.
This study tests whether a numbing injection near the pelvic floor plus physical therapy can prevent long-term pain after an episiotomy or first-time tear during vaginal delivery. It aims to help women recover more comfortably after childbirth.
Hear when a new Perineal Trauma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.