Clin2
NCT07684235Possibly a fitRecruiting

Long-term study of a weight-loss drug for trial graduates

ObesityOverweight

Treatments studied

Part of Hormones & metabolism clinical trials.

This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
3,200 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You must have completed the main MARITIME-1 trial and its week 72 visit.
  • You must not have stopped the study drug during the main trial.
  • You must be able to start this extension within 7 days of your week 72 visit.
  • You must not have a body mass index (BMI) lower than 18.5.
  • You must use approved birth control during treatment and for 16 weeks after your last dose.
  • You must not be pregnant, breastfeeding, or planning to become pregnant during the study period.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07037459Recruiting· Phase 3
A study of a new drug for heart failure with obesity

This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.

Birmingham, Alabama
NCT07770841Recruiting· Phase 3
Oral medication for weight loss study

This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.

Birmingham, Alabama
NCT07684144Recruiting· Phase 3
Long-term study of a weight-loss medication for people who completed an earlier trial

This study tests the long-term effects of a medication called maridebart cafraglutide for weight management. It is for people who already completed a 72-week study of this drug and want to continue treatment.

Gilbert, Arizona
NCT07832799Not yet recruiting· Phase 1
How two forms of a weight-loss drug enter the body

This study compares two versions of an investigational weight-loss injection to see if they are absorbed similarly. It is an early-stage trial for adults with a BMI of 25 or higher who want to help improve future treatments.

NCT07871409Not yet recruiting· Phase 3
Injectable weight-loss medicine for adults with obesity or overweight

This study tests whether people with obesity or overweight can safely and effectively give themselves the study medicine (called maridebart cafraglutide) at home using a pre-filled autoinjector pen. It is being studied as a weight-loss treatment for adults who have struggled to lose weight with diet and exercise alone.

The Villages, Florida
NCT07037433Recruiting· Phase 3
Heart protection study for people with heart disease and overweight

This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.

Daphne, Alabama

Hear when a new Obesity trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.