Clin2
NCT07684820Worth exploringRecruiting

A study of ExPD-101 for COPD with chronic bronchitis and frequent flare-ups

Chronic Obstructive Pulmonary Disease (COPD)

Part of Infections, Lungs & breathing clinical trials.

This study tests an experimental drug (ExPD-101) given daily as a pill for 52 weeks for people with COPD who have chronic bronchitis and frequent flare-ups. It compares the drug to a placebo (inactive pill) to see if it reduces flare-ups and improves symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
600 people
Ages
40 years to 85 years
Study type
Interventional

Who can take part

  • You have COPD with chronic bronchitis (a daily cough with phlegm for at least 3 months in the last year).
  • You have had at least 2 moderate or more than 1 severe COPD flare-up in the past year.
  • You are using a dual- or triple-combination inhaler (like LABA/LAMA, ICS/LABA, ICS/LAMA, or a triple inhaler) every day for at least 3 months.
  • You are a current or former smoker with at least a 10 pack-year history (1 pack a day for 10 years, for example).
  • You have not had a COPD flare-up or pneumonia in the last month before starting the study.
  • You do not have other lung diseases like asthma, active infection, or significant bronchiectasis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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