Leg-point injection to improve gut function in ventilator patients
Treatments studied
Part of Digestive system clinical trials.
This study tests whether injecting a common medication (neostigmine) into a specific point on the leg (called the Zusanli or ST36 point) can help improve bowel and stomach function in people on breathing machines. If you are on a ventilator and have constipation or slow digestion, this treatment might help get your gut working better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on a breathing machine (ventilator) and expected to need it for at least 2 days
- You have not had a bowel movement for 2 or more days, or your doctor finds too much fluid in your stomach
- You are 18 to 85 years old
- You have not had stomach or intestinal surgery in the past 8 weeks
- You do not have a history of severe gut problems like blockages, bleeding, or inflammatory bowel disease
- You do not have conditions that make neostigmine unsafe (e.g., asthma, slow heartbeat, seizures, or Parkinson's disease)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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