Brain effects of DMT in experienced users
Treatments studied
This study uses brain scans to see how a psychedelic drug called DMT affects brain activity. It is for people who have used psychedelics many times and are comfortable with the experience.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have used psychedelics (like LSD, magic mushrooms, or ayahuasca) at least 20 times in your life, including at least 5 times with DMT.
- You have used DMT at least once by smoking or inhaling, and you last used it between 3 months and 2 years ago.
- You are not taking antidepressants or other medications that affect serotonin or dopamine.
- You are willing to avoid alcohol, illicit drugs, and some supplements for a period around the study sessions.
- You can have an MRI scan (no metal implants or pacemaker) and are comfortable in a scanner.
- You do not have a current or recent mental health condition like depression, anxiety, bipolar disorder, or schizophrenia.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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