Study of efimosfermin for adults with cirrhosis from MASH
Treatments studied
Part of Digestive system clinical trials.
This trial tests a new drug, efimosfermin, to see if it is safe and effective for people with cirrhosis caused by MASH (a type of fatty liver disease). It may help improve liver health compared to a placebo.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with cirrhosis (scarring of the liver) due to MASH, confirmed by a liver biopsy.
- You have at least two signs of metabolic syndrome, such as high blood pressure, high blood sugar, or high cholesterol.
- You do not have other liver diseases or serious complications from liver disease.
- You do not have type 1 diabetes or major complications from type 2 diabetes.
- You do not drink excessive amounts of alcohol now or in the past.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether efimosfermin, an experimental drug, can safely help people with MASH (a fatty liver disease) that has led to cirrhosis (liver scarring) but the liver is still working well (compensated). Participants will be randomly assigned to receive the drug or a placebo.
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