Norepinephrine dose for low blood pressure during emergency belly surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether a 5 microgram or a 10 microgram dose of norepinephrine works better to treat low blood pressure that happens after starting anesthesia or during emergency abdominal surgery. It may help doctors choose the right dose to keep your blood pressure stable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18 or older) and have a physical status of ASA I, II, or III (meaning you are generally healthy to having a serious systemic disease).
- You are scheduled for emergency surgery on your abdomen.
- You do not have serious heart problems, such as a weak heart pump (ejection fraction below 45%), heart block, arrhythmias, or tight heart valves.
- You are not currently on a vasopressor (medicine to raise blood pressure).
- You are not pregnant or breastfeeding, and you do not have an allergy to the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two different doses of the drug noradrenaline to see which works better at preventing dangerously low blood pressure after spinal anesthesia for a planned C-section. This is for women who are at least 37 weeks pregnant and within a certain weight and height range.
This study tests a method to safely reduce (wean) norepinephrine, a blood-pressure–support medicine, in people who develop low blood pressure after heart surgery. It uses a monitoring index to help decide when it may be safer to lower the dose, aiming to improve recovery and reduce risks.
This trial tests whether a higher or lower dose of norepinephrine works better to treat dangerously low blood pressure that can happen during a C-section. If you are a healthy full-term mother having a planned C-section, you may be able to join.
This trial tests whether giving a small amount of norepinephrine (a blood-pressure medication) during surgery can help reduce the amount of IV fluids needed and lower the risk of lung complications after surgery in patients undergoing laparoscopic abdominal procedures.
This trial tests whether giving small doses of ephedrine during surgery can prevent dangerously low blood pressure in adults undergoing major abdominal surgery. It may help patients who are at risk for this complication.
This trial compares giving norepinephrine alone versus norepinephrine plus ephedrine to keep your blood pressure stable during a planned C-section under spinal anesthesia. It may help find the best way to prevent low blood pressure during delivery.
Hear when a new Hypotension on Induction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.