Cold therapy for pain after root canal re-treatment
Part of Brain & nervous system, Genetic & congenital, Pain clinical trials.
This study tests whether cold therapy (cryotherapy) can reduce pain after re-treating a root canal infection. It aims to see if this treatment changes certain natural chemicals in the body (PGE2 and NGF) that are linked to pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old and in good general health.
- You have a lower premolar tooth that had a root canal before and now needs re-treatment because of a painless infection at the root tip.
- You have not used antibiotics in the last month.
- You are not pregnant, breastfeeding, or have a serious medical condition like uncontrolled diabetes or autoimmune disease.
- You do not smoke more than 10 cigarettes a day and have not taken pain relievers in the last 24 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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