Gene activity study in BRCA carriers with and without early cell changes
Part of Cancer, Genetic & congenital, Women’s health & pregnancy clinical trials.
This study looks at gene activity in stored ovarian and fallopian tube tissue from people with and without BRCA gene mutations, to find early markers that might help prevent ovarian cancer. If you have a BRCA mutation, they are especially interested in a very early change called STIC, which can be a sign of future cancer risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old
- Have a documented BRCA gene test result (either a mutation or normal)
- Have never been diagnosed with ovarian, fallopian tube, or primary peritoneal cancer
- Have stored tissue samples from your ovaries (and fallopian tubes if available) that were removed in the past
- Have tissue that is normal (no other gynecologic cancer or abnormal growths besides STIC in one tube)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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