Medicine to reduce bleeding during fibroid surgery
Treatments studied
Part of Cancer, Skin clinical trials.
This study tests whether a medicine called terlipressin, given before surgery to remove uterine fibroids (myomectomy), can help reduce bleeding during the operation. If you are eligible, you may receive terlipressin or a placebo (a dummy medication) to see if it makes your surgery safer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have uterine fibroids that are causing symptoms such as heavy menstrual bleeding, pelvic pain or pressure, or infertility.
- Your largest fibroid is between 4 and 10 centimeters (about the size of a golf ball to a tennis ball).
- Your hemoglobin level (a measure of red blood cells) is 9 or higher.
- You are not pregnant and agree to use birth control during the trial.
- You have not had previous surgery for fibroids (myomectomy).
- You are not taking blood-thinning medications and do not have a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if the drug letrozole can improve symptoms like heavy bleeding and pelvic pain caused by uterine fibroids. You must be premenopausal with moderate to severe symptoms and not have very large fibroids or certain other conditions.
This trial compares two surgical techniques to reduce bleeding during surgery to remove fibroids (benign tumors) from the uterus. The goal is to find the safest, least-bloody approach for women who need this procedure.
This trial compares two injected medicines (terlipressin vs carbetocin) given into the uterus during open fibroid (myomectomy) surgery to see which one reduces blood loss and helps maintain hemoglobin. It may help patients by targeting lower bleeding during surgery.
This trial tests whether temporarily clamping the main blood vessels to the uterus during laparoscopic fibroid removal can reduce blood loss. It is for women with up to four fibroids who are planning this type of surgery.
This trial compares two medications (ergometrine and carbetocin) given during surgery to see which one is better at reducing bleeding while removing fibroids. Both drugs help the uterus contract to control blood loss.
This study tests if blocking blood flow to the uterus and ovaries during minimally invasive fibroid removal surgery helps reduce bleeding. It may be an option if you are having this type of surgery for large or numerous fibroids.
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