Medicine to reduce bleeding during fibroid surgery
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests a drug called terlipressin, which may help reduce bleeding during surgery to remove uterine fibroids. If you are having fibroid surgery, this study may help make your surgery safer with less blood loss.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have uterine fibroids that cause symptoms like heavy bleeding, pelvic pain, pressure, or infertility, and you are scheduled for myomectomy (surgery to remove fibroids).
- Your largest fibroid is between 4 and 10 centimeters in size.
- Your hemoglobin level is at least 9 grams per deciliter (a measure of your blood's oxygen-carrying capacity).
- You are not pregnant and are willing to use birth control if needed.
- You do not have bleeding disorders, are not on blood thinners (anticoagulants or antiplatelet drugs), and do not have certain heart or blood vessel conditions.
- You have not had fibroid surgery before, and you have not taken GnRH agonists or ulipristal acetate in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study compares two different medications given as shots during laparoscopic fibroid (myomectomy) surgery. The goal is to see which shot better reduces blood loss and helps keep hemoglobin (a blood oxygen-carrying protein) from dropping too much.
This trial compares two injected medicines (terlipressin vs carbetocin) given into the uterus during open fibroid (myomectomy) surgery to see which one reduces blood loss and helps maintain hemoglobin. It may help patients by targeting lower bleeding during surgery.
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This trial tests different methods to minimize blood loss during laparoscopic surgery to remove uterine fibroids. It may help women with heavy bleeding or trouble getting pregnant.
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