Botulinum toxin injections for hidradenitis suppurativa
Treatments studied
Part of Infections, Skin clinical trials.
This study tests whether botulinum toxin (Botox) injections can help treat hidradenitis suppurativa (HS), a skin condition with painful bumps. The goal is to see if blocking certain nerve signals can reduce HS flare-ups.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between the ages of 13 and 75.
- You have been diagnosed with hidradenitis suppurativa (HS) for at least 1 year.
- You have HS breakouts in at least two different areas of your body.
- You have tried oral antibiotics that didn't help enough, or your HS came back after stopping them.
- You have at least 5 painful bumps or sores from HS right now, but fewer than 20 draining tunnels.
- You are not pregnant or breastfeeding, and you don't have a nerve or muscle disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a drug called secukinumab (a type of biologic that targets inflammation) for people with moderate to severe hidradenitis suppurativa (HS). It may be an option if you have tried other treatments and they didn't work well.
This study tests a new medicine given by injection (anti-IL-17A/F antibody) combined with a laser treatment (non-ablative dot laser) for people with mild to moderate hidradenitis suppurativa (also called HS). The goal is to see if the combination is safe and works better than current options, and might help reduce pain and flare-ups.
This study tests a new injected medication (SPY072) for people with moderate to severe hidradenitis suppurativa (HS), a condition causing painful bumps and abscesses. The goal is to see if this treatment can reduce symptoms and improve quality of life.
This study looks at certain immune cells (called MAIT cells) in the skin of people with hidradenitis suppurativa, a painful skin condition. It will compare samples from people before they start a new biologic treatment, and may help doctors understand how these treatments work.
This study tests whether applying secukinumab as a topical cream or as a subcutaneous injection is more effective and safer for treating hidradenitis suppurativa (a skin condition causing painful lumps). It aims to find a better way to manage symptoms in people whose condition has not improved with standard treatments.
This study tests a new treatment that blocks a protein called type 1 interferon, which may reduce inflammation and pain in severe hidradenitis suppurativa. It is for people who have not improved with standard treatments like antibiotics or biologic drugs.
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