Treatment
Botulinum toxin type A clinical trials
We’re tracking 30 recruiting studies that include Botulinum toxin type A, each written for real people, not researchers, below.
Recruiting studies
- NCT06448676RecruitingPhase 4
Comparing botulinum toxin products for frown lines
This study compares different brands of Botox-like injections to see which works best for smoothing frown lines between the eyebrows. If you're a woman who has never had this treatment before, you may qualify.
AmsterdamAges 18 years+ - NCT06783114RecruitingPhase 2/Phase 3
Testing a new Botox-like injection for arm stiffness after stroke
This study tests an investigational botulinum toxin injection (YY001) to reduce muscle stiffness in the arm after a stroke. It may help you move your arm more easily and improve daily tasks.
Hefei, AnhuiAges 18–75 - NCT06465056RecruitingPhase 2
Botox for eyebrow lift scar healing
This study tests whether injecting Botulinum Toxin A (Botox) into the scar from an eyebrow lift surgery helps the scar heal better. Participants will be people who are already planning to have a direct eyebrow lift.
São PauloAges 18 years+ - NCT07561580Recruiting
Botulinum toxin for excessive forehead sweating
This trial tests whether botulinum toxin injections can reduce excessive sweating on the forehead. If your forehead sweats heavily despite using antiperspirants, this treatment might help you stay dry and more comfortable.
LatakiaAges 18–40 - NCT07665528Recruiting
Botox vs Botox with surgery for chronic anal fissure
This trial compares two treatments for a long-lasting anal fissure: Botox injections alone versus Botox combined with a small surgery (fissurectomy and anoplasty). It aims to see which works better and may help patients who have not healed with standard care.
Islamabad, FederalAges 18–65 - NCT07478822RecruitingPhase 3
Botulinum toxin study for arm spasticity after stroke
This study tests a new botulinum toxin injection (YY001) for adults whose arm muscles are tight or stiff after a stroke. It looks at whether repeated treatments help with daily activities like washing and dressing.
BeijingAges 18–75 - NCT06937944RecruitingPhase 3
New Botox-like injection for frown lines
This study tests a new botulinum toxin injection (similar to Botox) to see how well it smooths moderate to severe frown lines between the eyebrows. The treatment is given as a single injection and may help soften those lines for several months.
Beijing, Beijing MunicipalityAges 18–65 - NCT07233993Recruiting
Ultrasound-guided vs. standard Botox injections for cervical dystonia
This trial compares using ultrasound to guide Botox injections versus the usual method without ultrasound, to see if it improves outcomes for people with cervical dystonia.
MilanAges 18 years+ - NCT07242300RecruitingPhase 3
Testing a new botulinum toxin for arm stiffness after stroke
This trial tests a new injectable medication (Eveotox) to see if it can safely reduce arm or hand stiffness in people who have had a stroke. The goal is to improve daily activities like dressing or cleaning your hand.
Beijing, Beijing MunicipalityAges 18–80 - NCT05720065RecruitingPhase 2
Testing botulinum toxin A for jaw muscle pain
This trial studies whether botulinum toxin A (a type of muscle-relaxing medicine) can reduce jaw muscle pain and help explain why it happens. It focuses on people with specific jaw muscle pain patterns and tests outcomes after injection/biopsy.
Huddinge, Stockholm CountyAges 20–45 - NCT03198702RecruitingPhase 3
Early botulinum shots to prevent shoulder shape problems
This trial tests whether early injections of botulinum toxin into a baby’s arm muscles can prevent the shoulder from changing shape in infants with obstetrical brachial plexus palsy (OBPP). It also checks that the injections are safe and effective over time.
BrestAges 10 months–11 months - NCT03944876RecruitingPhase 3
Botulinum toxin to block a facial nerve for chronic cluster headaches
This trial tests whether injections of botulinum toxin type A can reduce frequent, severe cluster headache attacks by targeting a facial nerve area. It’s for people whose cluster headaches have not responded well—or have caused side effects—to standard preventive treatments.
HamburgAges 18–85 - NCT06296082RecruitingPhase 2/Phase 3
Dry Needling vs Botox for Post-Stroke Leg Stiffness
This study compares two treatments for leg stiffness after a stroke: dry needling (tiny needles placed in trigger points) and Botox injections. It may help you if you've had a first stroke within the past year and have mild to moderate tightness in the calf muscles that limits ankle movement.
Antwerp, FlandersAges 18–75 - NCT06878482RecruitingPhase 4
Botulinum toxin injection for severe leg artery disease
This trial tests whether a single injection of botulinum toxin (a muscle-relaxing substance) into the leg can improve blood flow and help heal wounds in people with severe blocked leg arteries who cannot have standard procedures like angioplasty.
Yongin-si, Gyeonggi-doAges 20 years+ - NCT07034547Recruiting
Botox for children with cerebral palsy
This study tests whether a Botox (botulinum toxin) injection can improve arm and leg movement in children with cerebral palsy. It is for kids ages 8–17 who have stiffness mainly on one side and can walk well.
Santiago, Santiago MetropolitanAges 8–17 - NCT07335367RecruitingPhase 2
PRP and Botox for hair loss: a study
This trial tests whether combining platelet-rich plasma (PRP) injections with botulinum toxin type A (Botox) can help regrow hair in people with male or female pattern baldness. It aims to see if this combination is safe and effective for treating androgenetic alopecia.
Guangzhou, GuangdongAges 18–60 - NCT07399860RecruitingPhase 2
Botox before hemorrhoid surgery to reduce pain after surgery
This trial tests whether injecting botulinum toxin (Botox) into the anal muscle before hemorrhoid removal surgery can lower pain after the operation. It is for people with advanced hemorrhoids that have not gotten better with other treatments and who are already planning to have surgery.
Moscow, MoscowAges 18 years+ - NCT06677216Enrolling by invitation
Botox for jaw muscle pain study
This study tests if Botox injections can reduce pain in the jaw muscles caused by a jaw joint disorder (TMD). If you have this type of pain and are interested in Botox treatment, you may be able to join.
Utrecht, UtrechtAges 18 years+ - NCT06410859Enrolling by invitationPhase 2
Botox injection for trigeminal neuralgia pain
This study tests a Botox injection (HengLi®) to see if it can reduce facial pain from trigeminal neuralgia. It is for people whose pain is not well controlled by standard medications.
Beijing, Beijing MunicipalityAges 18–75 - NCT04695600RecruitingPhase 2/Phase 3
Botox for swallowing problems after brain injury
This trial tests if Botox injections in the throat can help people who have trouble swallowing due to a brain condition like stroke. It aims to improve safety and ease of eating and drinking.
New Delhi, National Capital Territory of DelhiAges 14 years+ - NCT06293300RecruitingPhase 2
Botulinum toxin for light sensitivity after brain injury
This study tests if botulinum toxin type A (Botox) can reduce long-term light sensitivity in people who have had a traumatic brain injury at least a year ago. You must have had light sensitivity for 6 months or more and not have had Botox for face or mouth conditions before.
Miami, FloridaAges 18 years+ - NCT05502718Recruiting
Exercise program for cervical dystonia treated with botulinum toxin
This trial studies whether a structured exercise program can help people with cervical dystonia (involuntary neck muscle tightening) who are already being treated with botulinum toxin type A. It may help improve how you move and function, alongside your usual injections.
Ankara, AltındağAges 18 years+ - NCT06974617Recruiting
Nerve block vs. Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (sphenopalatine block) and Botox injections. It aims to see which one works better for reducing headache days.
CairoAges 18–65 - NCT07666347Recruiting
Botox and Hyaluronic Acid Injections for Knee Osteoarthritis
This study tests if injecting Botox and hyaluronic acid into the knee joint can reduce pain and improve function in people with advanced knee osteoarthritis. It compares this combination to a standard treatment.
Tanta, El-GharbiaAges 50 years+
What Botulinum toxin type A is being studied for
Conditions with recruiting Botulinum toxin type A studies.
Common questions
- Are there clinical trials studying Botulinum toxin type A?
- Yes. Clin2 currently lists 30 recruiting studies that include Botulinum toxin type A, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Botulinum toxin type A trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Botulinum toxin type A an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Botulinum toxin type A or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.