Study of NST-628 for recurrent grade 4 brain tumor
Part of Cancer clinical trials.
This study tests an experimental drug called NST-628 for people with a type of brain cancer (grade 4 glioma) that has returned or worsened after standard treatment. The drug is given before surgery, and you will have a biopsy or tumor removal to see how the drug works in your tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a grade 4 brain tumor (glioma) that has progressed after standard treatments like surgery and radiation with chemotherapy.
- You must have a tumor tissue sample that shows high levels of a protein called pERK.
- You must be scheduled for surgery to remove the tumor, and the tumor must be visible on an MRI with contrast.
- You must be 18 years or older and able to take oral medications.
- You must not have significant heart problems, other serious medical conditions, or active infections like HIV, hepatitis B, or hepatitis C.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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