Clin2
NCT07789184Possibly a fitNot yet recruiting

Surgery versus no surgery after successful conversion therapy for stomach cancer with peritoneal spread

Gastric CancerPeritoneal Metastasis

Part of Cancer, Digestive system clinical trials.

This trial compares having surgery to remove stomach cancer versus not having surgery in patients whose cancer in the abdominal lining responded well to initial treatment. The goal is to see which approach helps patients live longer and feel better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
170 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • You have stomach cancer that has spread to the lining of your abdomen (peritoneal metastasis), but no spread to other organs.
  • You have not had chemotherapy, targeted therapy, or immunotherapy before.
  • You are in generally good health (able to care for yourself, no serious heart or liver problems).
  • After initial treatment, a second look inside your abdomen shows the cancer is no longer visible in the lining.
  • You are willing to be randomly assigned to either surgery or no surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04843215Recruiting
Surgery comparison for advanced stomach cancer after initial surgery

This trial studies whether removing all of the fatty lining (omentum) or only part of it during surgery leads to better outcomes in people with advanced stomach cancer. It also checks that participants can safely have the same stomach-cancer chemotherapy plan after surgery.

Tianjin, Tianjin Municipality
NCT06768463Recruiting
Stomach cancer surgery after chemo for limited spread

This trial tests if surgery to remove the stomach and some tumors, after a few months of chemo, helps people whose stomach cancer has spread to only a few nearby spots (like the lining of the belly, liver, or lymph nodes) live longer compared to chemo alone.

Ho Chi Minh City, Ho Chi Minh
NCT07056010Recruiting
Minimally invasive surgery for advanced stomach cancer after chemoimmunotherapy

This trial tests a minimally invasive surgery for stomach cancer that has spread to lymph nodes near the main blood vessels (para-aortic area). The surgery is done after a combination of chemotherapy and immunotherapy to shrink the tumor. It aims to see if this approach is safe and effective.

Nanjing, Jiangsu
NCT03385018Recruiting
Laparoscopic total stomach surgery trial for stomach cancer

This trial studies whether a minimally invasive (laparoscopic) removal of the entire stomach, along with lymph node removal, can be done safely and effectively for certain stomach cancers. It may be an option if your cancer is in the stomach, has limited spread to nearby lymph nodes, and can be fully removed.

Seoul
NCT05537129Recruiting
Laparoscopic vs open stomach surgery for stomach cancer

This trial compares two ways surgeons remove the entire stomach (total gastrectomy): laparoscopic (small keyhole cuts) versus open surgery (one larger cut). It’s testing which approach is safer and works better for people with certain stages of stomach cancer.

Shanghai, Shanghai Municipality
NCT06054906Recruiting· Phase 2
Immunotherapy plus chemo before surgery for stomach cancer

This trial tests a combination of an immunotherapy drug (sintilimab) and a low-dose weekly chemotherapy regimen before surgery for locally advanced stomach cancer that can be removed. The goal is to see if this approach helps shrink the tumor and improve outcomes.

Shanghai

Hear when a new Gastric Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.