Clin2
NCT07790380Possibly a fitNot yet recruiting

Comparing a new drug to standard chemo for advanced esophageal cancer

Locally Advanced, Recurrent or Metastatic ESCC Patients Who Have Failed Prior PD-1/PD-L1 Inhibitors Combined With Platinum-based Chemotherapy

Part of Cancer, Digestive system clinical trials.

This trial tests a new drug called FH-006 against standard chemotherapy for people with advanced esophageal cancer that has stopped responding to previous treatment. The goal is to see if FH-006 can help control the cancer better or with fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
480 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have esophageal squamous cell carcinoma that is locally advanced, recurrent, or has spread to other parts of the body.
  • You have already been treated with a PD-1/PD-L1 inhibitor combined with platinum-based chemotherapy, and that treatment has stopped working.
  • You have at least one tumor that can be measured on a scan.
  • You are in generally good health, able to care for yourself, and have adequate organ function.
  • You have not had other cancer treatments within the last 4 weeks, and any side effects from prior treatments have mostly resolved.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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