Study of PKN605 in people with kidney problems
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests how the body handles an investigational drug called PKN605 in people with different levels of kidney function. It aims to see if the drug is safe and how it is processed when kidneys are impaired, which can help doctors decide the right dose for people with kidney disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old and weigh at least 110 pounds with a body mass index between 18 and 42.
- You have moderate or severe kidney disease (but you are not on dialysis), or you are a healthy person with normal kidney function.
- You have not had a kidney transplant or a nephrectomy (surgery to remove a kidney).
- You do not have a history of serious heart rhythm problems, long QT syndrome, or a family history of sudden cardiac death.
- If you are on medications for blood pressure or diabetes, your dose must have been stable for at least 4 weeks before the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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