Blood markers study for dravet syndrome
Part of Brain & nervous system clinical trials.
This study looks for certain substances in the blood (called biomarkers) that may show how Dravet syndrome affects the brain. The goal is to better understand the condition and possibly improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosis of Dravet syndrome, confirmed by a disease-causing change in the SCN1A gene
- Seizures started between 1 and 20 months of age, including fever-related or non-fever convulsions on one side or spreading to both sides
- No age limit – both children and adults can join
- For children, a parent or guardian must sign a consent form; older children and teens must also agree to participate
- Healthy volunteers (no neurological conditions) are also needed as a comparison group
- No other major illnesses like autoimmune disease, cancer, or neurodegenerative conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-phase trial tests an experimental medicine called RC001 in children with Dravet syndrome caused by SCN1A gene changes. The goal is to see if RC001 is safe and how the body processes it, with the hope of reducing seizures.
This trial tests the safety of a medicine called fenfluramine for children under 2 years old with Dravet syndrome. It aims to see if fenfluramine can help control seizures in very young children.
This study looks at what happens when children with Dravet or Lennox Gastaut syndrome switch from a homemade or artisanal CBD product to Epidiolex, a prescription CBD. The goal is to see if the switch is safe and helps control seizures.
This study looks at “GABA signals” in the body/brain to learn more about Dravet syndrome and how it may relate to seizures. If you have Dravet syndrome caused by a specific SCN1A gene change, you may be asked to provide genetic test results and help with study visits so researchers can compare biomarker readings.
This study follows children with Dravet syndrome caused by a specific SCN1A gene change to understand how the condition develops over time. It may help families know more about what to expect.
This study uses a special PET-MRI scan to look at a brain chemical pathway linked to serotonin (a mood-regulating substance) in people with Dravet syndrome or certain types of epilepsy, and in healthy volunteers. It may help understand how the brain works in these conditions.
Hear when a new Dravet Syndrome (DS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.