Clin2
NCT07801456Possibly a fitNot yet recruiting

Testing a higher dose of an experimental CMV vaccine in healthy adults

Cytomegalovirus (CMV)HIV (Human Immunodeficiency Virus)

Part of Immune system & allergy, Infections clinical trials.

This study tests a higher dose of an experimental vaccine (VIR-1388) that may help prevent infection with cytomegalovirus (CMV), a common virus that can be harmful to people with weakened immune systems and to unborn babies. The vaccine is given to healthy adults who already have CMV to see if it is safe and produces a good immune response.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
12 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You are between 18 and 55 years old.
  • You have had a CMV infection in the past (a simple blood test can confirm this).
  • You are in good general health, with no major medical conditions like diabetes, autoimmune diseases, or bleeding disorders.
  • You have not taken certain antiviral medications (like acyclovir or ganciclovir) within the past 30 days.
  • You have not received an experimental vaccine in the past year (some exceptions may apply).
  • You are willing to use condoms during the study and avoid donating blood, sperm, or tissues until the study ends.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06075745Recruiting· Phase 2
CMV Vaccine Study for Liver Transplant Candidates

This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.

Birmingham, Alabama
NCT07390474Recruiting· Phase 1
HIV vaccine safety and immune response study for healthy adults

This study tests two experimental mRNA-based HIV vaccines to see if they are safe and create an immune response. It is for healthy adults aged 18 to 55 who do not have HIV.

Atlanta, Georgia
NCT07818824Not yet recruiting· Phase 1
Cmv and tb vaccine study in healthy adults

This trial tests an experimental vaccine called VIR-1778 that may help protect against infections caused by two viruses: cytomegalovirus (CMV) and tuberculosis (TB). The study looks at whether the vaccine is safe and how well it works in healthy adults.

Iquitos
NCT03354728Recruiting· Phase 1/Phase 2
Vaccine trial for children with CMV after stem cell transplant

This trial studies a vaccine designed to help the body fight cytomegalovirus (CMV) in children who test positive for CMV and are about to receive a donor stem cell transplant. If it works, it may reduce CMV-related illness during recovery after transplant.

Duarte, California
NCT07818915Not yet recruiting· Phase 1
Safety study of an experimental medication in healthy adults

This study tests an experimental medication in healthy volunteers to see how it is processed by the body and whether it is safe. You may not receive direct benefit, but your participation helps find better treatments for people with HIV.

NCT07020533Recruiting· Phase 1
CMV vaccine for stem cell transplant recipients

This trial tests a vaccine designed to boost immunity against CMV (a common virus) and prevent active CMV infection in people receiving a half-matched stem cell transplant. It may help protect you from CMV-related complications after transplant.

Duarte, California

Hear when a new Cytomegalovirus (CMV) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.