Early antibiotic treatment guided by a blood test to prevent severe infection
Treatments studied
Part of Infections clinical trials.
This study tests whether giving an early antibiotic (meropenem) based on a new blood test (PSP) can prevent serious infections (sepsis) in people who come to the emergency department with signs of infection. The goal is to find out if this approach helps them get better faster and avoid more severe illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have signs of a possible infection, such as fever, fast heartbeat, or breathing trouble, and a specific blood test result (PSP) that shows high risk of sepsis.
- You must not already have severe organ failure or need intensive support like a breathing machine.
- You must be able to take the antibiotic meropenem (no serious allergy to it or related drugs like penicillin).
- You must not be pregnant or breastfeeding, and you must not be taking certain medicines (probenecid, valproic acid, or warfarin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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