Fecal transplant for ulcerative colitis comparing donor types
Treatments studied
Part of Digestive system clinical trials.
This trial tests fecal microbiota transplantation (a procedure that puts healthy donor bacteria into your gut) for left-sided ulcerative colitis. It compares results using donors from two different backgrounds to see if one works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have ulcerative colitis affecting the left side of your colon.
- You have active symptoms (not in remission), with a moderate severity score of 3 to 10 on the Mayo scale.
- You are only using mesalazine (a common anti-inflammatory colitis medicine) and not other stronger drugs for your colitis.
- You are not pregnant or planning pregnancy soon.
- You do not have a history of bowel surgery, toxic megacolon, perianal disease, or serious heart, lung, kidney disease, or cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
This trial screens people as potential donors for a fecal microbiota transplant program used for ulcerative colitis. It checks safety and eligibility so the transplant process is as safe as possible for people with active disease.
This trial tests whether one or multiple fecal transplants from a healthy donor can help treat both a recurring C. diff infection and active ulcerative colitis. It aims to find the best schedule for the procedure.
This trial tests whether a stool transplant (fecal microbiota transplantation) can help manage active ulcerative colitis. You would receive a transplant from a healthy donor to see if it improves your symptoms.
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