Clin2
NCT07841093Possibly a fitNot yet recruiting

A study of a new pill for swelling due to kidney disease

Renal EdemaNephrogenic Edema

Treatments studied

Part of Kidney & urinary clinical trials.

This study tests an experimental pill (JMKX003142) to see if it can reduce swelling in people with kidney disease (renal edema) who are already taking water pills. Participating may help reduce fluid buildup and improve comfort, but it's only for patients whose kidney function is not too low.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old.
  • You must have swelling (edema) caused by kidney disease.
  • Your kidney function must be at a certain level (doctors will check with a blood test).
  • You must already be taking a water pill (diuretic), either one type or a combination, and be on a stable dose without changes during the study.
  • You must not be on dialysis or expected to need it soon.
  • You must be able to sense thirst and drink fluids normally.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06648876Not yet recruiting· Phase 1
Study of YG1699 for people with diabetes and kidney disease

This study tests a new medicine called YG1699 to see how it works in people who have both diabetes and kidney disease, including those on dialysis. It may help control blood sugar, but we need to learn more about its effects.

Shanghai, Shanghai Municipality
NCT06800651Recruiting· Phase 2
A new drug for fast-growing polycystic kidney disease

This trial tests a drug (JMKX003142) for people with autosomal dominant polycystic kidney disease that is getting worse quickly. It may help slow down kidney damage.

Beijing, Beijing Municipality
NCT07565441Not yet recruiting· Phase 1
Testing how a new drug interacts with other drugs in healthy adults

This study is for healthy volunteers to see how a new experimental drug (JMKX003142) interacts with other drugs in the body. It helps find the right dose for future patients.

NCT06321250Recruiting· Phase 1
Study of a new tablet for advanced kidney cancer

This study tests a new tablet (JMKX003948) for people with advanced clear cell kidney cancer. It aims to see if the drug is safe and how well it works.

Beijing
NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload

This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.

Dallas, Texas
NCT07470177Not yet recruiting· Phase 1
Healthy adult study of a new medicine's effect on heart rhythm

This study tests a new medicine (JMKX003142) in healthy adults to see if it affects the heart's rhythm. If you qualify, you may help determine whether the drug is safe to use in future patients.

Hear when a new Renal Edema trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.