Clin2
NCT04759274Possibly a fitRecruiting

Personalized water pill dosing support for kidney and fluid overload

EdemaHypervolemiaChronic Kidney DiseasesNephrotic Syndrome

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have either heavy protein in your urine or advanced kidney disease
  • You currently have fluid overload (swelling in legs, belly fluid, or fluid around the lungs)
  • Your “dry weight” is at least 5 pounds less than your current enrollment weight
  • You can measure and record home blood pressure and body weight, and you have a working smartphone
  • You are not pregnant and you are between 100 and 300 pounds

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07631780Not yet recruiting
Sodium-guided water pill treatment for heart failure

This trial tests if using urine sodium levels to guide diuretic (water pill) dosing during hospital care for worsening heart failure can improve outcomes. The goal is to help doctors adjust treatment more effectively to clear extra fluid from the body.

Aktobe
NCT07099885Recruiting
Urine test to guide water pill treatment for heart failure

This study tests a simple urine test to help doctors choose the best dose of water pills (diuretics) for people hospitalized with heart failure and leg swelling. The goal is to relieve congestion faster and more safely.

Wroclaw, Dolnosląskie
NCT07841093Not yet recruiting· Phase 3
A study of a new pill for swelling due to kidney disease

This study tests an experimental pill (JMKX003142) to see if it can reduce swelling in people with kidney disease (renal edema) who are already taking water pills. Participating may help reduce fluid buildup and improve comfort, but it's only for patients whose kidney function is not too low.

Shanghai
NCT06166654Recruiting· Phase 4
Better water pill therapy for acute heart failure

This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.

Hvidovre, Capital Region of Denmark
NCT06092437Recruiting
Testing a personalized diuretic plan for acute heart failure

This trial is testing whether a diuretic (water pill) dose tailored to each patient works better for treating fluid buildup during a heart failure flare-up. It may help you get the right amount of medication faster and avoid complications.

Heerlen, Limburg
NCT07469722Not yet recruiting· Phase 2/Phase 3
Lung ultrasound to guide water pill treatment for heart failure

This study uses lung ultrasound to help doctors decide how to give water pills to people with heart failure who have extra fluid in their body. It may help reduce symptoms and improve recovery from a heart failure episode.

Porto Alegre, Rio Grande do Sul

Hear when a new Edema trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.