Clin2
NCT07845357Possibly a fitNot yet recruiting

Switching glaucoma drops to preservative-free ZOLYMBUS

Eye Drops Self-instillationGlaucomaDry Eye

Part of Eyes & vision clinical trials.

This study tests whether switching from a standard glaucoma eye drop (which contains preservatives) to a preservative-free version called ZOLYMBUS can help with both eye pressure control and dry eye symptoms. If you have both glaucoma and dry eye, this switch might reduce irritation while keeping your pressure stable.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years or older
  • Have glaucoma or high eye pressure
  • Currently taking a single prostaglandin eye drop for glaucoma
  • Eye pressure well-controlled (≤21 mmHg)
  • Dry eye symptoms for at least 6 months
  • Moderate to severe dry eye (confirmed by tests)
  • Vision correctable to 20/40 or better
  • Willing to stop wearing contact lenses for 24 hours before screening and throughout the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04957329Recruiting· Phase 4
Latanoprost eye drops: with or without preservative

This study compares two versions of latanoprost eye drops—one that contains a preservative and one that is preservative-free. It aims to see how each version affects the eye’s “goblet cells,” which help keep the eye surface healthy.

Glostrup Municipality, Danmark
NCT07113210Recruiting· Phase 4
Quality of life with Qlosi eye drops for presbyopia

This trial tests whether a new prescription eye drop called Qlosi improves the quality of life for people with presbyopia (age-related trouble seeing up close). You will use the drops regularly and answer questions about your vision and daily activities.

Medina, Minnesota
NCT06379685Not yet recruiting· Phase 1
Testing a new eye drop for safety compared to a common brand

This study tests a new eye drop called PRO-190 to see if it's safe and comfortable for the eyes, comparing it to a common artificial tear (Systane Ultra). It is for healthy people and may help if you have dry or irritated eyes.

NCT07074782Not yet recruiting
Using eye drops to protect nerve cells in glaucoma

This study looks at whether certain glaucoma eye drops might help protect the nerve cells in your eye over time. If you've been using the same type of eye drop for a few years, researchers will review your past eye tests to see how your vision and eye health have changed.

Bonn
NCT06017362Recruiting· Phase 4
Insulin drops for dry eye in glaucoma patients

This study tests whether insulin eye drops can safely help dry eye in people who also use eye drops for glaucoma. It may offer a new option if you have both conditions and your eye pressure is stable.

Madrid, Madrid
NCT07661329Recruiting· Phase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure

This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.

Beverly Hills, California

Hear when a new Glaucoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.