Clin2
NCT07848074Possibly a fitNot yet recruiting

Lowering the dose of abrocitinib for controlled eczema

Atopic Dermatitis

Treatments studied

Part of Genetic & congenital, Immune system & allergy, Skin clinical trials.

This study tests whether gradually lowering the dose of abrocitinib can keep your eczema under control while reducing side effects. It is for people with moderate-to-severe eczema who have already been on abrocitinib 200 mg daily for at least 3 months and whose skin is currently well controlled.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with moderate to severe eczema for at least 6 months.
  • You have been taking abrocitinib 200 mg every day for at least 3 months.
  • Your eczema has been well controlled (very mild or clear) at two doctor visits at least one month apart.
  • You do not have another skin condition that could interfere with eczema assessment.
  • You are not taking immunosuppressive medications for another condition.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07823595Not yet recruiting· Phase 3
Abrocitinib for eczema in young children

This study tests a daily pill, abrocitinib, to see if it safely reduces severe eczema (atopic dermatitis) in children aged 2 to under 6 years. It may help when creams or other treatments haven't worked well enough.

NCT05689151Recruiting
Abrocitinib for adult moderate to severe atopic eczema

This study tests how well abrocitinib (a prescription medicine) works for adults with moderate to severe atopic dermatitis (atopic eczema). You may join if you meet the study’s health and consent requirements and your doctor believes abrocitinib is an appropriate option for you.

Amiens, Somme
NCT06899204Recruiting
Abrocitinib for atopic dermatitis after biologic therapy

This study looks at how well abrocitinib (a daily pill) works for people with moderate to severe eczema who have already tried biologic medicines and didn't get enough relief. It aims to see if this treatment can help you better manage your eczema.

San Diego, California
NCT06807281Recruiting· Phase 3
Abrocitinib for children with eczema: long-term study

This study tests the long-term safety and effectiveness of abrocitinib (Cibinqo) for children aged 6 to 12 with moderate to severe eczema that hasn't improved with creams. It may help their skin clear and reduce itching.

Birmingham, Alabama
NCT06389136Recruiting· Phase 3
Study of upadacitinib for eczema after dupilumab didn't work

This trial tests if a pill called upadacitinib (a JAK inhibitor) can help adults with moderate-to-severe atopic dermatitis (eczema) that didn't improve enough with dupilumab. You may be able to join if your eczema is still active despite using dupilumab for at least 4 months.

Birmingham, Alabama
NCT06004986Recruiting· Phase 4
Lowering Dupilumab Dose in Controlled Eczema

This study looks at whether people with well-controlled eczema can safely lower their dose of dupilumab (an injected medication). It aims to see if a reduced dose still keeps eczema under control.

Amsterdam, North Holland

Hear when a new Atopic Dermatitis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.