How rilzabrutinib tablet is processed in people with severe kidney disease
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at how a medicine called rilzabrutinib (taken as a tablet) is processed in the body when the kidneys are severely damaged compared to when they work normally. It helps researchers understand if the dose needs to be adjusted for people with kidney problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe kidney disease (but are not on dialysis) or you have normal kidney function
- You are not on dialysis
- You weigh between 50.0 and 115.0 kg (if male) or 40.0 and 100.0 kg (if female), and your BMI is between 18.0 and 40.0
- You have not had a serious infection requiring IV antibiotics or hospitalization in the past 4 weeks (if you have severe kidney disease)
- You are willing to follow contraception rules (if applicable)
- You can stop smoking during the study (occasional smokers are okay)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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