Clinical trials
Renal Impairment clinical trials
Below are recruiting renal impairment clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07559396RecruitingPhase 1
Safety study of INCB123667 in adults with severe kidney disease
This study tests how a new experimental drug (INCB123667) works and is tolerated in adults with severe kidney problems or end-stage kidney disease. Researchers want to understand how the drug moves through the body and whether it's safe for people in your situation.
Miami Lakes, FloridaAges 18–85 - NCT07017933Recruiting
Kidney support device for heart surgery patients
This trial tests a new device that helps support kidney function during heart surgery. It is for people with mild to moderate kidney problems who are having bypass or valve surgery.
Weston, FloridaAges 22–85 - NCT07227922RecruitingPhase 1
Study of clofutriben in people with kidney impairment
This study tests how the drug clofutriben is processed in people with moderate kidney impairment compared to those with normal kidneys. It helps determine if dose adjustments are needed in kidney patients.
Orlando, FloridaAges 18–83 - NCT07694869RecruitingPhase 1
Study of ammoxetine tablets in people with moderate kidney problems
This trial tests how a new drug called ammoxetine works in people with moderate kidney impairment compared to those with normal kidney function. It aims to find the right dose and understand how the drug is processed by the body.
Hefei, AnhuiAges 18–75 - NCT07793929RecruitingPhase 1
Kidney function and study drug levels
This study checks how different levels of kidney function affect the levels of a new investigational drug called Ribupatide in the blood. It helps doctors understand how the drug works in people with various kidney conditions.
Orlando, FloridaAges 18–85 - NCT06708520RecruitingPhase 1
Rupatadine safety study in people with kidney problems
This trial checks how the allergy medicine rupatadine moves through the body and how safe it is for people with different levels of kidney function, compared to people with healthy kidneys.
GaiaAges 18 years+ - NCT05428631Recruiting
Monitoring device tested in severe kidney and heart failure
This study checks how safe a small heart-pressure monitoring device is for people with advanced heart failure and severe kidney problems. It looks at whether doctors can continuously track heart filling/pressure to help manage symptoms and reduce risks.
Nîmes, GardAges 18–85 - NCT05326399Recruiting
Kidney biopsies after liver transplant for new kidney problems
This trial studies kidney biopsies in people who had a liver transplant and then developed new signs of kidney damage. The goal is to better understand what’s causing the problem and how to guide next steps.
ShanghaiAges 18–75 - NCT07141030RecruitingPhase 1
Study of GZR18 in people with and without kidney problems
This trial tests how a new drug called GZR18 (given as an injection) affects the body in people with different levels of kidney function. It aims to find the right dose and check for side effects, which could help guide treatment for people with kidney issues.
BeijingAges 18–75 - NCT07763418RecruitingPhase 1
Kidney function study of golcadomide
This study tests how a new drug, golcadomide, works in people with severe kidney problems compared to those with normal kidneys. It helps see if the drug needs different dosing for patients with kidney issues.
Chandler, ArizonaAges 18–84 - NCT07585760RecruitingPhase 2
Two-drug treatment for newly diagnosed myeloma with kidney problems
This trial tests a combination of two drugs, CM336 and isatuximab, for people newly diagnosed with multiple myeloma who also have kidney problems caused by the disease. The goal is to see if this combination can help control the myeloma while also improving kidney function.
TianjinAges 18–80 - NCT06386796Recruiting
Using ultrasound to predict kidney trouble in high-risk patients
This study uses a simple ultrasound test (kidney artery scan) to see if it can predict kidney problems early in people who are very ill. It may help doctors protect your kidneys during your hospital stay.
Aswān, Aswan GovernorateAges 18–80 - NCT04196244RecruitingPhase 4
IV-contrast CT vs no-contrast CT for urgent abdominal pain
This study compares two types of CT scans—using IV contrast dye versus not using dye—in people who need an emergency abdominal scan but have reduced kidney function. It aims to see which approach is safer and works well enough to help doctors find the cause.
EspooAges 18 years+ - NCT07807059RecruitingPhase 1
Study of HRS-4729 injection in healthy people and those with kidney problems
This study is testing a new injectable medicine (HRS-4729) to see how the body processes it in people with healthy kidneys and in those with kidney problems. If you join, you will receive a single dose and have your blood and urine checked over time to measure the drug levels.
Chengdu, SichuanAges 18–65 - NCT07741604RecruitingPhase 1
Kidney function safety study for RO7795081
This study tests a new medicine called RO7795081 in people with different levels of kidney function, including those with kidney problems and those with normal kidneys. It aims to see how safe the medicine is and how the body processes it, which helps doctors decide safe dosing for people with kidney issues.
Miami Lakes, FloridaAges 18–85 - NCT07734610RecruitingPhase 1
Testing Nemtabrutinib in People with Severe Kidney Disease
This trial tests a new medicine (nemtabrutinib) in people with severe kidney disease to see how the body handles it. The study helps doctors decide safe doses for people with kidney problems.
Miami Lakes, FloridaAges 18–80 - NCT07715175RecruitingPhase 1
D-2570 in people with different kidney function
This study tests how a new drug, D-2570, is processed by the body in people with normal or reduced kidney function. It aims to understand if kidney function affects how the drug works, which could help guide dosing.
Hefei, AnhuiAges 18–70 - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sun City, ArizonaAges 18 years+ - NCT00948116Recruiting
Blood and urine tests to predict kidney injury in diabetes
This study checks whether a set of blood and urine tests can predict “acute kidney injury” (a sudden worsening of kidney function) earlier in people with diabetes who are undergoing a heart procedure. If the tests work, they may help doctors spot kidney trouble sooner and protect your kidneys.
LondonAges 18 years+ - NCT07315360RecruitingPhase 1
How a new medicine works in people with reduced kidney function
This study tests how the body processes the experimental medicine PF-07328948 in people with different levels of kidney function. It may help find the right dose for people with kidney disease.
Lake Forest, CaliforniaAges 18–80 - NCT07006688RecruitingPhase 1
Ivosidenib for IDH1-mutated cancers with liver or kidney issues
This trial tests an oral drug (ivosidenib) for people with IDH1-mutated cancers who also have liver or kidney problems. It aims to find the right dose and see how safe and effective it is for these patients.
Atlanta, GeorgiaAges 18 years+ - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT06085183RecruitingPhase 4
Study of a dye to check ureters during surgery in people with kidney problems
This trial tests a blue dye (Bludigo) to help doctors see if the ureters are open during surgery. It is for people with normal or reduced kidney function who need a procedure where the ureters are checked.
Albany, New YorkAges 18–85
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Renal Impairment trials by city
Studies with a site in or near these metro areas.
Renal Impairment trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for renal impairment?
- Yes. Clin2 currently lists 26 recruiting renal impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a renal impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a renal impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.