Replacing the mitral valve without open-heart surgery
This trial tests a new device that replaces a damaged mitral heart valve without open-heart surgery. It aims to help people whose leaky valve causes symptoms like shortness of breath or fatigue, and who cannot have standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a severe leak in your mitral valve (the valve between two left heart chambers).
- You are at least 65 years old.
- You have symptoms like tiredness or trouble breathing, and your heart team says you cannot have usual valve repair or replacement surgery.
- You are willing to come back for follow-up visits after the procedure.
- Your heart's shape and structure are suitable for this new device.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial studies a new way to replace a damaged mitral heart valve using a catheter (a thin tube), instead of open-heart surgery. It may help people who have severe leaking of the mitral valve but are considered too high-risk for surgery.
This trial tests a new device that is placed using a thin tube through a vein in the leg to repair a leaky mitral valve in people with heart failure. The goal is to see if it can reduce symptoms and improve quality of life beyond what usual medications can do.
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
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This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
This early-stage trial tests a new device called the ReValve System that replaces a damaged mitral valve (the valve that controls blood flow in your heart). The study is for people with a weakened heart who have leaking mitral valves and are experiencing heart failure symptoms.
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