Clip device for leaking mitral valve in heart failure
Part of Heart & circulation clinical trials.
This trial tests a new device that is placed using a thin tube through a vein in the leg to repair a leaky mitral valve in people with heart failure. The goal is to see if it can reduce symptoms and improve quality of life beyond what usual medications can do.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have heart failure with symptoms like shortness of breath or fatigue even on optimal medications (NYHA class II-IV).
- Your mitral valve leak is at least moderate to severe, caused by your heart muscle's weakness, not by a structural valve problem.
- Your heart's pumping function is at least 20% and the size of your left heart chamber is within limits.
- You have elevated BNP or NT-proBNP levels or have been hospitalized for heart failure in the past year.
- You are not pregnant, and if you are of childbearing age, you agree to use contraception for the study duration.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a catheter-based procedure to treat a leaky mitral valve (either FMR or DMR, depending on the group you’re in). It may help reduce symptoms and improve heart function in people who are sick from valve leakage but are able to undergo this specific approach.
This trial is testing a new device to help people with severe mitral regurgitation (a leaky heart valve) who cannot have open-heart surgery or a valve clip. The device is placed using a thin tube through a blood vessel, and aims to improve symptoms and quality of life.
This trial tests a new device, called MRace, that is placed with a thin tube into the heart to fix a leaky mitral valve. It's for people whose valve is too complex for the usual clip repair, and who are too high-risk for open-heart surgery.
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
This trial tests a catheter-based procedure (putting a small device through blood vessels) to repair a leaking mitral valve caused by heart muscle problems. It aims to reduce symptoms and improve heart function and safety in people who are still having heart failure symptoms despite standard treatment.
This trial tests a new device for people whose mitral valve leaks badly (grade 3+ or 4+) and who are not candidates for surgery. The device aims to fix the leak through a less invasive approach, and the study checks if it's safe and works well in daily life.
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