Liver transplant for colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial studies whether a liver transplant can be a safe and effective treatment for people with colorectal cancer that has spread only to the liver and cannot be removed with surgery. It aims to remove the liver tumors and replace the liver with a healthy one, potentially offering a chance for a longer, cancer-free life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have colorectal cancer that has spread only to the liver, and the liver tumors cannot be surgically removed.
- You had surgery to remove the original colorectal tumor at least 6 months ago, with clear margins and no signs of the cancer coming back in the colon or rectum.
- Your cancer has responded to at least 6 months of systemic therapy (like chemotherapy), shown by imaging and a blood test for CEA.
- You have no cancer spread outside the liver, are generally in good health (able to do daily activities), and have a CEA level below 80.
- Your tumor type is specific: it is not BRAF-mutated and is microsatellite stable, and you have a potential living liver donor who meets medical and legal criteria.
- An official transplant committee has approved you as a good candidate for a liver transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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