Clinical trials
Acute Severe Ulcerative Colitis clinical trials
Below are recruiting acute severe ulcerative colitis clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07632573RecruitingPhase 1
Safety Study of BDHK-2009 Tablets in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called BDHK-2009 in healthy volunteers with no major illnesses. Researchers want to make sure the drug is safe and well-tolerated before testing it in people with medical conditions.
Hangzhou, ZhejiangAges 18–55 - NCT07154784Enrolling by invitationPhase 2/Phase 3
Fecal transplant for long-term ulcerative colitis treatment
This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
Seoul, Dongjak-guAges 10–80 - NCT06095128RecruitingPhase 4
Vedolizumab and tofacitinib study for ulcerative colitis
This trial tests if combining two medicines, vedolizumab and tofacitinib, helps control moderate to severe ulcerative colitis. It may be an option if other treatments, like anti-TNF drugs, haven't worked well for you.
Dothan, AlabamaAges 18–65 - NCT04183608RecruitingPhase 4
Telemonitoring and education to guide treatment for ulcerative colitis
This trial tests whether “treat-to-target” care—guided by regular symptom checks, telemonitoring, and patient education—works better than standard follow-up when starting adalimumab for ulcerative colitis. It aims to help control inflammation more effectively and reduce flare-ups.
Cholet, Maine Et LoireAges 18–75 - NCT06159244Recruiting
Gut bacteria in severe alcoholic hepatitis
This trial looks at the gut bacteria (microbiome) in people with severe alcoholic hepatitis to understand how it affects the illness. It may help doctors find better ways to treat this condition.
Amiens, PicardieAges 18–75 - NCT05987852Recruiting
Hyperbaric oxygen therapy for ulcerative colitis flare
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) can help people hospitalized with a moderate to severe ulcerative colitis flare get better faster. You will receive the therapy along with standard steroid treatment.
Birmingham, AlabamaAges 18–85 - NCT07501078RecruitingPhase 2
Can seaweed mineral supplement prevent J-pouch inflammation?
This trial tests whether a supplement called Aquamin, made from seaweed, can help prevent pouchitis—inflammation of the J-pouch—in people with ulcerative colitis. If you have had J-pouch surgery within the last 8 months, you may be eligible.
Ann Arbor, MichiganAges 5–80 - NCT06632691Recruiting
Virtual reality headset for rectosigmoidoscopy in ulcerative colitis
This trial tests if using a virtual reality (VR) headset during a rectosigmoidoscopy (a scope exam of the lower gut) makes the procedure more comfortable and acceptable for people with ulcerative colitis. The VR headset may help distract you and reduce discomfort during the exam.
La Roche-sur-YonAges 18 years+ - NCT07245394Recruiting
Switching to guselkumab for inflammatory bowel disease after ustekinumab
This trial tests whether switching from the drug ustekinumab to another drug called guselkumab can help people with active inflammatory bowel disease (IBD) who didn't get enough benefit from ustekinumab. It focuses on people with Crohn's disease or ulcerative colitis who still have signs of inflammation in their gut.
Calgary, AlbertaAges 18 years+ - NCT07564609Enrolling by invitation
Infliximab injection therapy outcomes in inflammatory bowel disease
This study tracks how patients with Crohn's disease or ulcerative colitis respond to infliximab (a biologic medication) given as injections under the skin after an initial IV dose. Researchers want to understand which patients benefit most and for how long.
AmiensAges 18 years+ - NCT07257588Enrolling by invitation
Hyperbaric oxygen for severe ulcerative colitis
This study tests whether adding hyperbaric oxygen therapy—breathing pure oxygen in a pressurized chamber—to standard care can help people with a severe flare of ulcerative colitis (a type of inflammatory bowel disease). It may reduce inflammation and speed up recovery.
Xi'an, ShaanxiAges 18 years+
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Common questions
- Are there clinical trials for acute severe ulcerative colitis?
- Yes. Clin2 currently lists 35 recruiting acute severe ulcerative colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute severe ulcerative colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute severe ulcerative colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.