Clinical trials
Ulcerative Colitis Chronic clinical trials
Below are recruiting ulcerative colitis chronic clinical trials, each written for real people, not researchers. We’re tracking 64 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07577856RecruitingPhase 3
Testing JNJ-78934804 for moderate to severe ulcerative colitis
This study tests a new drug called JNJ-78934804 to treat ulcerative colitis (inflammation of the colon and rectum) that is moderate to severe and hasn't responded well to standard treatments. The goal is to see if this drug can reduce inflammation and improve symptoms.
Anaheim, CaliforniaAges 18 years+ - NCT07786389Enrolling by invitationPhase 1/Phase 2
Seaweed supplement for ulcerative colitis inflammation
This study tests whether a supplement made from seaweed (fucoidan) can help reduce gut inflammation in people with mild to moderate ulcerative colitis. If you join, you'll take the supplement and have your symptoms and blood levels checked.
Lahore, Punjab ProvinceAges 18–64 - NCT07652294Enrolling by invitationPhase 2
Long-term safety of antibodies for IBD maintenance
This trial is testing long-lasting antibodies given alone or in combinations to keep IBD under control over the long term. It's for people who already did well in the initial study and want to continue treatment.
Lancaster, CaliforniaAges 18 years+ - NCT07726888Recruiting
Guselkumab for moderate-to-severe ulcerative colitis
This study tests a drug called Guselkumab (already approved for other conditions) for treating moderate to severe ulcerative colitis. It aims to see how safe and effective the drug is in real-world patients who have not had success with other treatments.
Wenzhou, ZhejiangAges 18 years+ - NCT07686081RecruitingPhase 3
Testing ponesimod for moderate to severe ulcerative colitis
This trial tests an oral medication called ponesimod for people with ulcerative colitis that hasn't responded well to other treatments. It aims to see if ponesimod can reduce inflammation and improve symptoms.
Chula Vista, CaliforniaAges 18–75 - NCT07724990Recruiting
Probiotic for gut health in mild-to-moderate colitis
This trial tests a specific probiotic (a type of beneficial bacteria) to see if it can help people with mild to moderate ulcerative colitis by improving the balance of gut microbes. It may be an option if you have not used many advanced treatments before.
Roma, RMAges 18–80 - NCT07243639Recruiting
Etrasimod for elderly patients with ulcerative colitis
This trial tests an oral medication called etrasimod for elderly patients with active ulcerative colitis. It aims to see if the drug is safe and effective in reducing inflammation and symptoms.
Komagane, NaganoAges Any age - NCT04844606RecruitingPhase 3
Mirikizumab for kids with ulcerative colitis or Crohn’s
This study checks whether continuing mirikizumab (a medicine that calms gut inflammation) helps children with ulcerative colitis or Crohn’s disease after prior study treatment. It aims to see if staying on the medicine is beneficial and safe over time.
San Francisco, CaliforniaAges 2–19 - NCT05610956RecruitingEarly Phase 1
Empagliflozin for mild-to-moderate ulcerative colitis
This early trial studies whether empagliflozin can improve ulcerative colitis symptoms and is safe for people with mild to moderate disease. If it works, it may reduce ongoing colon inflammation and help people feel better.
TantaAges 18–70 - NCT05666960RecruitingPhase 1
Study drug R-3750 for mild to moderate ulcerative colitis
This Phase 1 study tests whether R-3750 is safe in people with mild to moderate ulcerative colitis and looks for early signs it could help. You may be able to join if you have stable treatment, confirmed diagnosis, and meet several health and medication timing rules.
Valencia, CaliforniaAges 18–65 - NCT05791487Recruiting
Diet plus oral budesonide for mild to moderate ulcerative colitis
This trial studies whether combining a specific diet with an oral steroid called budesonide can calm symptoms in people with mild to moderate ulcerative colitis. It may help reduce inflammation in the colon while building on stable current treatments.
AfulaAges 17–65 - NCT06213857RecruitingPhase 2
Silymarin for ulcerative colitis
This study tests whether silymarin (an extract from milk thistle) can help treat ulcerative colitis when added to your usual treatment. It may reduce inflammation and oxidative stress in the colon.
AsyutAges 18–65 - NCT06228352Recruiting
Bile acids and gut bacteria in C. difficile with ulcerative colitis
This study looks at how bile acids and gut bacteria relate to C. difficile infection in children with ulcerative colitis. It aims to find better ways to predict and treat these infections.
ParisAges Up to 17 years - NCT06311123Recruiting
Study of Ozanimod's Effects on Immune Cells in Ulcerative Colitis
This study looks at how the medicine ozanimod works in people with active ulcerative colitis. Researchers will use a special blood test to understand how the drug affects your immune system.
San Diego, CaliforniaAges 18 years+ - NCT06420492RecruitingPhase 2
New treatments for severe ulcerative colitis flare
This trial tests new therapies for people with a severe UC flare that hasn't improved after 5 days of high-dose steroids. It aims to find more effective options to control symptoms and avoid hospitalization.
Chestnut Hill, MassachusettsAges 18–75 - NCT06453317RecruitingPhase 2
Comparing UC treatments: infliximab vs ustekinumab vs both
This study compares an existing UC medication (infliximab) with a newer one (ustekinumab) and a combination of both. The goal is to see which works best for moderate to severe UC when other treatments have failed.
LodzAges 18–64 - NCT07692165RecruitingPhase 1/Phase 2
Testing INT-210 capsules for active ulcerative colitis
This trial tests an experimental capsule called INT-210 for people with active ulcerative colitis (UC) who haven't improved enough with standard treatments. It aims to see if the drug can help control symptoms and improve the condition.
Guangzhou, GuangdongAges 18–75 - NCT07296315RecruitingPhase 2
Testing a new treatment for mild-to-moderate ulcerative colitis
This study tests an investigational drug for people with active mild-to-moderate ulcerative colitis. It aims to see if the drug can improve symptoms without needing advanced treatments like biologics.
Miami, FloridaAges 16 years+ - NCT06515210Recruiting
Fibre supplement for ulcerative colitis inflammation
This study tests whether a special fibre supplement can reduce inflammation in people with active ulcerative colitis. You take the supplement daily for a few weeks, and researchers check how it affects your symptoms and gut health.
Edmonton, AlbertaAges 14 years+ - NCT06598943RecruitingPhase 2
Study of two new drugs for ulcerative colitis
This study tests two experimental drugs, Eltrekibart and Mirikizumab, for adults with moderate to severe ulcerative colitis who have not responded well to other treatments. The goal is to see if these drugs can help control the disease.
Chandler, ArizonaAges 18–75 - NCT06865417RecruitingPhase 3
Filgotinib for children and teens with ulcerative colitis
This trial tests if filgotinib, a pill for adults with ulcerative colitis, works in children and teenagers. It may help those whose current treatments are not working well enough or cause side effects.
Brussels, Brussels CapitalAges 8–18 - NCT06867094RecruitingPhase 2
Study of SAR441566 for Ulcerative Colitis
This trial tests a new medicine called SAR441566 for people with moderate-to-severe ulcerative colitis (UC). It may help reduce symptoms like bleeding and diarrhea if other treatments haven't worked well enough.
Sun City, ArizonaAges 18–75 - NCT07115862Recruiting
Pomegranate juice study for mild to moderate ulcerative colitis
This trial tests if drinking pomegranate juice can help people with mild to moderate ulcerative colitis. You may be eligible if your diet is low in fruits and vegetables and you are on stable medications.
Los Angeles, CaliforniaAges 18 years+ - NCT07374471RecruitingPhase 1/Phase 2
Testing MB-001 for moderate to severe ulcerative colitis
This study tests an investigational drug called MB-001 for people with moderate to severe ulcerative colitis who have already tried standard treatments without success. It aims to see if the drug is safe and helps control inflammation.
ChisinauAges 18–75
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Ulcerative Colitis Chronic trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for ulcerative colitis chronic?
- Yes. Clin2 currently lists 64 recruiting ulcerative colitis chronic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ulcerative colitis chronic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ulcerative colitis chronic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.