Clinical trials
Severe Asthma clinical trials
Below are recruiting severe asthma clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07735494Recruiting
Physical activity study for people with severe asthma starting tezepelumab
This study tests whether a physical activity program can help people with severe asthma achieve better control and reduce flare-ups when added to a new treatment called tezepelumab.
LeedsAges 18–70 - NCT07532265RecruitingPhase 2
Testing a New Drug for Hard-to-Control Asthma
This study tests whether a new drug called frevecitinib can help people with severe asthma that isn't well controlled even with strong inhaled steroid medications. The goal is to see if it reduces asthma attacks and improves breathing.
Lancaster, CaliforniaAges 18–75 - NCT06681545Recruiting
Living with severe asthma as a young adult
This study explores what it's like to live with severe asthma as a young adult. It uses interviews or focus groups to understand your experiences, to help improve care for others like you.
Manchester, GreaterAges 16–25 - NCT07139899Recruiting
Mucus Plugs and Lung MRI in Severe Asthma
This study is looking at how mucus plugs in the airways affect lung function in people with severe asthma. If you are about to start a new injectable asthma treatment (dupilumab, tezepelumab, or benralizumab), you may be able to join and get a special type of lung MRI to see how your lungs are doing.
Durham, North CarolinaAges 18–65 - NCT07292805Recruiting
Bronchial thermoplasty for severe asthma
This study tests a procedure called bronchial thermoplasty for adults with severe asthma that is not controlled with standard treatments. It aims to see if this can help reduce asthma attacks in people who have already tried or cannot use biologic therapies.
AmsterdamAges 18 years+ - NCT07328035Recruiting
Asthma remission in adults with severe asthma
This study looks at whether adults with severe asthma in Thailand can reach a state where their asthma symptoms go away (remission). You may join if you have severe asthma and can do the required breathing tests.
Pathum ThaniAges 18 years+ - NCT07655037Recruiting
Exercise study for severe asthma
This study tests if a personalized exercise program can help adults with severe asthma who are starting a new biologic treatment. It aims to improve symptoms and quality of life.
HelsinkiAges 18 years+ - NCT03984253Recruiting
Swiss Severe Asthma Register for adults and children
This study set up a long-term asthma registry to better understand people with severe asthma and what treatments they use. If you fit the asthma severity requirements, you may be asked for consent and basic health information so the team can follow your asthma over time.
Liestal, Basel-LandschaftAges 1 year+ - NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+ - NCT05761028RecruitingPhase 2/Phase 3
CM310 for moderate to severe asthma despite current inhalers
This study tests CM310 to see if it can improve asthma in people with moderate to severe asthma who are still having uncontrolled symptoms and severe flare-ups despite regular inhaler treatment. You may be eligible if your lung function and asthma control tests fit the study limits and you’ve had a recent severe exacerbation.
Beijing, BeijinAges 12–75 - NCT07372287RecruitingPhase 3
Study of CM326 for moderate to severe asthma
This trial tests an investigational drug called CM326 for people with moderate to severe asthma that is not well controlled with current treatments. It aims to see if CM326 can help reduce asthma attacks and improve breathing.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06456450Recruiting
Taiwan severe asthma biologic registry study
This study is creating a registry to track the long-term safety and effectiveness of biologic treatments for severe asthma in Taiwan. If you are taking a biologic like omalizumab, mepolizumab, or benralizumab, joining this registry helps doctors learn how well these medicines work over time.
TaichungAges 18 years+ - NCT06625216Recruiting
Severe asthma registry in Italy
This study collects information from people with severe asthma across Italy to better understand the condition and improve treatment. By joining, you help researchers learn what works best for people like you.
Rozzano, MilanoAges 13 years+ - NCT06903780Recruiting
Survey on biologic treatments for severe asthma
This study surveys patients who have been on a biologic treatment for severe asthma for at least 6 months but not longer than 18 months. It aims to understand their experience, including those who did not respond well to the treatment.
Exeter, DevonAges 18 years+ - NCT06472310Recruiting
Study of severe asthma in Russia (CORSAR)
This study looks at the health records of people in Russia with severe, uncontrolled asthma to understand their symptoms and treatments better. It does not involve any new medicine or treatment.
AstrakhanAges 18 years+ - NCT07276724RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma
This trial tests an add-on medicine called GB-0895 for people with severe asthma that is not well controlled with current treatments. It aims to see if adding this drug can reduce asthma attacks and improve breathing.
Northridge, CaliforniaAges 12–80 - NCT07359846RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma in adults and teens
This trial tests an add-on treatment called GB-0895 for people with severe asthma that is not well controlled with current medications. It aims to see if adding this drug can reduce asthma attacks and improve lung function.
Bakersfield, CaliforniaAges 12–80 - NCT04045587Recruiting
Registry for severe asthma in adults in Canada
This is a research registry that collects health information from adults with severe asthma to better understand how the condition behaves and how treatments are used. You may be able to take part if your asthma is considered severe and is not well controlled.
Edmonton, AlbertaAges 18 years+ - NCT06035289Recruiting
Severe asthma registry for children and adults
This registry collects information about children and adults with severe asthma that is not well controlled with standard treatments. The goal is to better understand severe asthma and improve care.
AltdorfAges 6 years+ - NCT07363642RecruitingPhase 3
Tezepelumab for severe asthma
This study tests a drug called tezepelumab for people with severe asthma that is not well controlled with current treatments. It aims to see if adding this drug can reduce asthma attacks and improve symptoms.
BeijingAges 12–80 - NCT06916104Enrolling by invitation
Allergies and biotherapy in severe asthma
This study looks at whether having a respiratory allergy affects how well biotherapy works for people with severe asthma. It includes adults already on biotherapy and followed at Poitiers University Hospital.
PoitiersAges 18 years+ - NCT07786870Recruiting
Understanding airway proteins in asthma
This study examines a protein called TSLP that may play a role in asthma inflammation. By looking at different versions of TSLP in your airway samples, researchers hope to learn more about asthma and potentially guide future treatments.
Warsaw, WarsawAges 18 years+ - NCT07582211Recruiting
BPAP breathing support for severe asthma attacks in children
This study tests whether a special breathing mask (BPAP) can help children ages 5–17 who come to the emergency room with severe asthma attacks. The mask gently pushes air into the lungs to help them breathe more easily.
New York, New YorkAges 5–17 - NCT06811740Enrolling by invitation
Treating severe asthma by focusing on key health issues
This trial looks at people with severe asthma that is hard to control. It aims to find and treat specific health problems that make asthma worse, by doing a detailed check-up and using treatments that are right for you.
Beijing, Beijing MunicipalityAges 18 years+
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Severe Asthma trials by city
Studies with a site in or near these metro areas.
Severe Asthma trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for severe asthma?
- Yes. Clin2 currently lists 67 recruiting severe asthma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe asthma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe asthma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.