Clinical trials · Massachusetts
Alcohol Use Disorder clinical trials in Massachusetts
We’re tracking 18 recruiting alcohol use disorder studies with a site in Massachusetts — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07219966RecruitingPhase 3
Study of Brenipatide for alcohol use disorder
This trial tests an injectable medicine called brenipatide to help people with moderate-to-severe alcohol use disorder reduce or stop drinking. It is for adults who are motivated to change their drinking habits.
Boston, MassachusettsAges 18–75 - NCT07219953RecruitingPhase 3
Testing brenipatide for alcohol use disorder
This study tests an experimental medicine called brenipatide to help people reduce or stop drinking. It involves getting a daily injection and completing check-ins and questionnaires over several months.
Boston, MassachusettsAges 18–75 - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
Fall River, MassachusettsAges 18–75 - NCT05138614Recruiting
Help for people with opioid use disorder and mental health needs
This trial studies a program meant to improve treatment access and support recovery for people with opioid use disorder who also have mental health symptoms. It may help if you are new to the program or recently relapsed, or if mental health symptoms have worsened—even without a relapse.
Holyoke, MassachusettsAges 18 years+ - NCT05929677RecruitingEarly Phase 1
Study tests effects on impulsivity and how alcohol feels
This early-phase study looks at how alcohol affects impulsivity (tendency to act quickly) and people’s subjective experiences. You may be able to join if you drink regularly and meet the study safety rules.
Boston, MassachusettsAges 21–25 - NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Boston, MassachusettsAges 14–21 - NCT06727331RecruitingPhase 2
Tirzepatide for alcohol use recovery
This trial tests if tirzepatide, a medication that helps with appetite and blood sugar, can help people with alcohol use disorder drink less or stop drinking. You would visit the clinic regularly and receive the drug or a placebo.
Boston, MassachusettsAges 18 years+ - NCT07232641Recruiting
How pandemic rules affected opioid addiction treatment in the VA
This study looks at how changes in federal and state rules about medications for opioid use disorder during the pandemic affected veterans. It uses information already in your VA records, so there are no extra visits or tests needed.
Boston, MassachusettsAges 18 years+ - NCT07420283RecruitingPhase 2
Study of Brenipatide for opioid use disorder
This trial tests a new medicine called Brenipatide for people with opioid use disorder who are already taking buprenorphine but still occasionally use non-prescribed opioids. It aims to see if the study drug can help reduce opioid use.
Boston, MassachusettsAges 18–75 - NCT07092059Recruiting
Smartphone app for stimulant use disorder
This study tests if a smartphone app can help people with stimulant use disorder stay on track. It may be a good option if you're leaving inpatient care or starting outpatient treatment.
Boston, MassachusettsAges 18 years+ - NCT05934305Recruiting
Help for shame and stigma in HIV and substance use
This study tests whether a program can reduce shame and stigma for people living with HIV who also have a substance use disorder. It may help you feel less judged and cope better, while supporting HIV care.
Boston, MassachusettsAges 18 years+ - NCT06994962Recruiting
Smartphone app to reduce heavy drinking in young adults
This study tests a smartphone app designed to help young adults (ages 18–25) drink less alcohol. If you're a heavy drinker and want to use technology to cut back, this app might be a good fit for you.
Boston, MassachusettsAges 18–25 - NCT07269119Recruiting
Pilot study of a Deaf-friendly alcohol treatment
This study tests a new way to help Deaf adults who use ASL and have problem drinking. It is done over Zoom and is designed to be accessible.
Shrewsbury, MassachusettsAges 18 years+ - NCT05910580Recruiting
Screening and support for alcohol and substance risk in adults
This study aims to improve care access and outcomes for adults who screen positive for risky alcohol or drug use. If you qualify, you may be offered ways to connect to support during your reproductive years.
Worcester, MassachusettsAges 18 years+ - NCT07503067Recruiting
Understanding substance use consequences
This study looks at the experiences and consequences of substance use. It is for people who either use substances, care for someone who does, or have a close friend or family member who does.
Belmont, MassachusettsAges 18 years+ - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT06373016Recruiting
Ketone drink study for stable bipolar disorder
This study tests whether a ketone drink can change how the body uses energy in people with bipolar disorder. It may help understand new ways to manage the condition.
Belmont, MassachusettsAges 18–45 - NCT06991205Recruiting
Web mind-body program for pain and substance use
This trial tests a web-based mind-body program to help people who have ongoing arm or hand pain and also use substances like alcohol or cannabis. It aims to improve resilience and reduce pain without requiring in-person visits.
Boston, MassachusettsAges 18 years+
Alcohol Use Disorder trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting alcohol use disorder studies listed above.
- Adams Clinical · 3 studies
- Brigham and Women's Hospital · 2 studies
- K2 Medical Research - Foxborough · 2 studies
- Massachusetts General Hospital · 2 studies
- McLean Hospital · 2 studies
- Northeastern University · 2 studies
- At-Home Study (6 Liberty Sq, #2102)
- Athinoula A. Martinos Center for Biomedical Imaging
What taking part in a alcohol use disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Alcohol Use Disorder trials in other states
Common questions
- Are there alcohol use disorder clinical trials in Massachusetts?
- Yes. We're currently tracking 18 recruiting alcohol use disorder studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a alcohol use disorder study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New alcohol use disorder studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.