Clinical trials · Connecticut
Alcohol Use Disorder clinical trials in Connecticut
We’re tracking 30 recruiting alcohol use disorder studies with a site in Connecticut — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Connecticut
- NCT06136195RecruitingPhase 1
Mavoglurant for alcohol craving in heavy drinkers
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
New Haven, ConnecticutAges 21–50 - NCT06070649RecruitingPhase 1
DMT for Alcohol Use Disorder
This trial tests whether a single dose of DMT, a psychedelic, can help people with alcohol use disorder. It's a small early-phase study to see if the treatment is safe and promising.
New Haven, ConnecticutAges 21–65 - NCT06584448Recruiting
Drinking, acetate, and stress study
This study looks at how acetate (a substance produced when the body breaks down alcohol) affects stress and drinking. It tests if giving acetate can help people with alcohol use disorder (AUD) reduce their drinking.
New Haven, ConnecticutAges 18–60 - NCT04793685RecruitingPhase 2
Prazosin for alcohol withdrawal symptoms in alcohol use disorder
This study tests whether prazosin can reduce symptoms that happen when someone stops or cuts back on heavy drinking. It may help people with moderate-to-severe alcohol use disorder who also have alcohol withdrawal symptoms.
New Haven, ConnecticutAges 18–70 - NCT03764098RecruitingPhase 2
Guanfacine to reduce heavy drinking in adults with alcohol use disorder
This Phase 2 study tests whether guanfacine can reduce drinking in women and men who drink heavily and meet criteria for alcohol use disorder. It also looks at how the medicine affects drinking patterns in a controlled setting.
New Haven, ConnecticutAges 21–70 - NCT05827159RecruitingPhase 3
Medications started in the ER for alcohol use disorder
This study tests whether starting certain medications in the emergency room can help people with moderate to severe alcohol use disorder reduce heavy drinking and withdrawal problems after they leave the ER. It compares outcomes for participants who receive the study medications soon after an ER visit.
New Haven, ConnecticutAges 18–80 - NCT05042102RecruitingPhase 2
Donepezil plus brain training for alcohol use disorder
This Phase 2 study tests whether donepezil, along with structured cognitive (brain) training, can improve outcomes for people with alcohol use disorder. It will measure whether this combination helps after recent heavy drinking, while tracking safety over about 13 weeks.
West Haven, ConnecticutAges 18–80 - NCT05576350Recruiting
Coaching to reduce risky drinking and HIV risk
This study tests an intervention (coaching/skills training) to help reduce risky alcohol use and reduce behaviors that increase HIV risk. It may help you if you drink in an at-risk way and may benefit from HIV prevention like PrEP.
New Haven, ConnecticutAges 18–35 - NCT05781009RecruitingPhase 2
Pregnenolone treatment for alcohol use disorder
This Phase 2 study tests pregnenolone to help reduce or improve alcohol use disorder symptoms. It looks for adults who drink regularly and meet diagnostic criteria for moderate to severe alcohol use disorder, while excluding people with certain other substance use, medicines, or serious mental/medical conditions.
New Haven, ConnecticutAges 18–70 - NCT05913752RecruitingPhase 1/Phase 2
Test drug CMND-100 in people with alcohol use disorder
This early study tests the safety and dosing of CMND-100 in first-time participants, including people with alcohol use disorder (AUD) and some healthy volunteers. It may help researchers understand whether the drug is safe, and how it might affect alcohol use in AUD.
New Haven, ConnecticutAges 18–60 - NCT05957159RecruitingEarly Phase 1
Testing an alcohol brain imaging study based on opioid receptor balance
This early-phase study looks at how the brain’s opioid receptor balance may be different in people with alcohol use disorder (AUD), using brain scans and blood testing. It may help researchers understand why some people respond differently to alcohol and related treatments.
New Haven, ConnecticutAges 21–70 - NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06371404Recruiting
Brain imaging study of stress and alcohol use disorders
This study uses a special brain scan to look at how stress and alcohol use affect the brain. It may help people with PTSD, alcohol use disorder, or healthy volunteers understand these conditions better.
New Haven, ConnecticutAges 18–70 - NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Farmington, ConnecticutAges 14–21 - NCT06963476Recruiting
Magnetic brain stimulation for substance use
This study uses a gentle magnetic stimulation (rTMS) to help people who are already in treatment for alcohol or opioid addiction. The goal is to see if adding rTMS can reduce cravings and improve recovery.
Hartford, ConnecticutAges 18–60 - NCT07029529RecruitingPhase 2
Apremilast for alcohol use disorder
This study tests whether a drug called apremilast can help people who drink heavily reduce their alcohol use. You will take the medication daily for several weeks and attend study visits to track your progress.
New Haven, ConnecticutAges 21–65 - NCT07118839RecruitingPhase 2/Phase 3
MDMA therapy for veterans with PTSD and alcohol use
This study tests whether MDMA-assisted therapy can help veterans who have both PTSD and alcohol use disorder. If you have tried a standard therapy before and want to reduce or stop drinking, this treatment may offer a new option.
West Haven, ConnecticutAges 18 years+ - NCT07223983RecruitingPhase 1
Semaglutide for alcohol use disorder after weight loss surgery
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with alcohol use disorder who have had gastric bypass or sleeve gastrectomy in the past 7 years. It may reduce alcohol cravings or drinking.
New Haven, ConnecticutAges 18 years+ - NCT07488819Recruiting
Brain imaging study for people with PTSD or alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with PTSD or alcohol use disorder. It may help researchers understand these conditions better.
New Haven, ConnecticutAges 18–70 - NCT07520292RecruitingPhase 1
Testing NTX-2001 to reduce drinking in alcohol use disorder
This study tests whether a new medication called NTX-2001 can help people with alcohol use disorder drink less. Researchers will measure how the drug affects alcohol consumption and safety in adults aged 21–60.
New Haven, ConnecticutAges 21–60 - NCT07525258Recruiting
Improving alcohol use disorder care for liver disease patients
This trial tests a new approach to help healthcare providers better support patients with alcohol-related liver disease who struggle with alcohol use. The study aims to make treatment easier to access and more effective within Yale's hospital system.
New Haven, ConnecticutAges 18 years+ - NCT07221383Enrolling by invitation
A smartphone app to help reduce heavy drinking
This study tests a smartphone program to help people who want to cut back on heavy drinking. It focuses on delivering support via text messages over the course of a month.
New Haven, ConnecticutAges 18 years+ - NCT06160284RecruitingPhase 1
Psilocybin for brain healing in opioid recovery
This study tests whether psilocybin, a psychedelic substance, can help change brain connections in people recovering from opioid use disorder. It involves brain scans and careful medical monitoring to explore new treatment options.
New Haven, ConnecticutAges 25–55 - NCT06489782Recruiting
New approach to test alcohol use disorder medications
This study tests a new way to quickly screen medications for alcohol use disorder (AUD). You will have lab sessions where your drinking is monitored to see how different medicines affect your alcohol use.
New Haven, ConnecticutAges 21–65
Alcohol Use Disorder trials by city in Connecticut
Where these studies are running in Connecticut
Institutions with a site for the recruiting alcohol use disorder studies listed above.
- Yale University · 11 studies
- Connecticut Mental Health Center · 3 studies
- VA Connecticut Healthcare System, West Haven Campus · 3 studies
- Yale School of Medicine · 3 studies
- Yale New Haven Hospital · 2 studies
- Hartford Healthcare
- Magnetic Resonance Research Center (MRRC) at The Anlyan Center
- UConn Health
What taking part in a alcohol use disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Alcohol Use Disorder trials in other states
Common questions
- Are there alcohol use disorder clinical trials in Connecticut?
- Yes. We're currently tracking 30 recruiting alcohol use disorder studies with a site in Connecticut, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a alcohol use disorder study in Connecticut?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Connecticut to take part?
- Not necessarily. These studies have a site in Connecticut, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a alcohol use disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New alcohol use disorder studies open in Connecticut regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.