Clinical trials · North Carolina
Alzheimer’s disease clinical trials in North Carolina
We’re tracking 32 recruiting alzheimer’s disease studies with a site in North Carolina — including Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05980949RecruitingPhase 3
Long-term safety study of KarXT for Alzheimer's psychosis
This trial tests the long-term safety of an investigational drug called KarXT for people with psychosis caused by Alzheimer's disease. It is for those who have already completed a previous KarXT study and want to continue treatment.
Shelby, North CarolinaAges 55–90 - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT05641688RecruitingPhase 3
PET brain scan study for people with terminal illness
This Phase 3 study tests an amyloid/tau PET brain imaging agent (called [18F]PI-2620). It aims to see how well the scan helps with brain pathology findings in people who are expected to have a life expectancy of 1 year or less.
Charlotte, North CarolinaAges 50 years+ - NCT06496425Recruiting
Exercise for protecting memory in older adults
This study tests whether a 12-month exercise program can help protect memory and thinking skills in older adults who have noticed changes in their memory. You would be asked to exercise at home and attend some group classes.
Greensboro, North CarolinaAges 65 years+ - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Monroe, North CarolinaAges 55 years+ - NCT07021040Recruiting
Nasal biopsy study for Alzheimer's and smell disorders
This study takes a small tissue sample from inside your nose to look for changes linked to Alzheimer's disease or smell problems. It may help us better understand how these conditions affect the brain.
Durham, North CarolinaAges 18 years+ - NCT07425106Enrolling by invitation
Comparing a low-cost eye scanner for Alzheimer's research
This study uses a special, low-cost eye scanner to look at the back of the eye (retina) in people with early Alzheimer's or mild memory problems. It aims to find changes that might help with early detection.
Durham, North CarolinaAges 18–85 - NCT03848312RecruitingPhase 3
Preventing Alzheimer’s with brain training for older adults
This Phase 3 study tests whether structured computer brain-training can help prevent Alzheimer’s-related thinking problems. You may be more likely to benefit if your thinking is currently normal, and you can safely do the computer exercises every schedule the study requires.
Durham, North CarolinaAges 65 years+
Alzheimer’s disease trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting alzheimer’s disease studies listed above.
- Duke University Medical Center · 3 studies
- AMC Research, LLC
- American Carolina Clinical Research LLC
- Duke University Health System
- Local Institution
- Local Institution - 1221
- Local Institution - 1252
- Monroe Biomedical Research
What taking part in a alzheimer’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Alzheimer’s disease trials in other states
Common questions
- Are there alzheimer’s disease clinical trials in North Carolina?
- Yes. We're currently tracking 32 recruiting alzheimer’s disease studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a alzheimer’s disease study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a alzheimer’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New alzheimer’s disease studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.