Clinical trials · Raleigh–Durham, NC
Alzheimer’s disease clinical trials in Raleigh–Durham
We’re tracking 13 recruiting alzheimer’s disease studies with a site in or near Raleigh–Durham — including Phase 1 and Phase 2 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT06808984RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's disease
This trial tests an investigational drug called BMS-986368 to see if it can safely reduce agitation in people with Alzheimer's disease. You may be able to join if you have Alzheimer's with confirmed biomarkers and experience agitation that has been going on for at least 4 weeks.
Raleigh, North CarolinaAges 55–90 - NCT05010603Recruiting
Studies families to understand late-onset Alzheimer’s
This study focuses on people with late-onset Alzheimer’s (and some similar memory diseases) and uses a close family “informant” to share what they’ve noticed. It may help researchers learn more about these conditions and how they progress in families.
Raleigh, North CarolinaAges 55 years+ - NCT06657768RecruitingPhase 1
Study of LY4006895 for healthy people and those with early Alzheimer's
This trial tests a new medicine called LY4006895 in two groups: healthy volunteers and people with early symptomatic Alzheimer's disease. It aims to see how the drug works in the body and if it might help memory and thinking.
Durham, North CarolinaAges 45–85 - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Durham, North CarolinaAges 55–90 - NCT07021040Recruiting
Nasal biopsy study for Alzheimer's and smell disorders
This study takes a small tissue sample from inside your nose to look for changes linked to Alzheimer's disease or smell problems. It may help us better understand how these conditions affect the brain.
Durham, North CarolinaAges 18 years+ - NCT06297590RecruitingPhase 1
First human study of a new Alzheimer's drug
This study tests an experimental drug (LY3954068) for people with early Alzheimer's disease. It aims to see if the drug is safe and may slow memory loss. You'll need a PET scan to measure tau protein in the brain and have a study partner who can help attend appointments.
Durham, North CarolinaAges 50–85 - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT07425106Enrolling by invitation
Comparing a low-cost eye scanner for Alzheimer's research
This study uses a special, low-cost eye scanner to look at the back of the eye (retina) in people with early Alzheimer's or mild memory problems. It aims to find changes that might help with early detection.
Durham, North CarolinaAges 18–85 - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT06565169Recruiting
Helping primary care doctors support advance care planning for dementia
This study tests a training tool to help primary care teams talk about future care wishes with people who have Alzheimer's or related dementias. It aims to improve advance care planning for older adults with dementia.
Chapel Hill, North CarolinaAges 18–99 - NCT06840587Recruiting
Connect-Home: Alzheimer's and related dementias study
This trial tests a program to help people with dementia and their caregivers prepare for a safe move from a skilled nursing facility to home or another care setting. It aims to improve the transition and support both the patient and caregiver.
Chapel Hill, North CarolinaAges 19 years+ - NCT07094516RecruitingPhase 2
Testing VHB937 for early Alzheimer's disease
This trial tests a new medicine, VHB937, in people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow down memory loss and thinking problems.
Chapel Hill, North CarolinaAges 50–85 - NCT05973448Enrolling by invitation
Nightlight Falls Prevention for People With Dementia
This study tests a simple plan to help prevent falls in people who have dementia. You may be able to join if you live in a participating assisted living community and meet the safety and room rules.
Chapel Hill, North CarolinaAges 18 years+
Hear when a new Alzheimer’s disease trial opens near Raleigh–Durham, NC
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Alzheimer’s disease trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting alzheimer’s disease studies listed above.
- Duke University Medical Center · 4 studies
- University of North Carolina at Chapel Hill · 3 studies
- Duke University · 2 studies
- Duke Early Phase Research Unit
- North Carolina State University
- UNC Health Rex
- UNC Investigational Drug Service Pharmacy
What taking part in a alzheimer’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting alzheimer’s disease studies in North Carolina.
Common questions
- Are there alzheimer’s disease clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 13 recruiting alzheimer’s disease studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a alzheimer’s disease study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a alzheimer’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New alzheimer’s disease studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.