Clinical trials
Anastomotic Leak clinical trials
Below are recruiting anastomotic leak clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06862479Enrolling by invitation
Comparing a stent to other endoscopic leak treatments
This trial compares a special stent (the Luso-Cor Stent) to other endoscopic procedures to treat leaks or abnormal connections after certain stomach or esophageal surgeries. It aims to find the best way to fix these complications using a scope.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07467980Recruiting
Measuring oxygen in the colon during bowel surgery
This study tests a new way to measure oxygen levels inside the colon during surgery, right after the surgeon reconnects the bowel. It may help doctors see if the new connection is healing well.
Nashville, TennesseeAges 18 years+ - NCT07295236Recruiting
Vacuum therapy for a leak after stomach surgery
This trial tests whether a treatment called endoscopic vacuum therapy can help heal a small leak that can happen after stomach removal surgery. If you are stable and the leak is small, this treatment may help you avoid more surgery.
KyivAges 18–90 - NCT07351071Recruiting
Study of Signia circular stapler in left colon and rectal surgery
This study is testing a new circular stapler, called the Signia, used to reconnect the bowel during planned left-sided colon or rectal surgery. It aims to see how well the device works in everyday hospital settings.
New Haven, ConnecticutAges 18 years+ - NCT07449208Recruiting
Esophagectomy leak risk registry study
This study follows people having surgery to remove part of the esophagus (esophagectomy) who are at higher risk for a leak where the esophagus is reconnected. The goal is to learn more about who develops leaks and how to prevent them.
Basking Ridge, New JerseyAges 18 years+ - NCT06553261Recruiting
Leakage after right colon surgery study
This study looks at how often leaks happen after planned surgery on the right side of the colon (the part that connects to the small intestine). It may help doctors understand risks better.
ViennaAges 18 years+ - NCT07464600Recruiting
CRP testing to predict leaks after colon surgery
This trial checks if a simple blood test for CRP (a marker of inflammation) after colorectal surgery can help predict if a patient might develop a leak where the bowel is reconnected. If you are having planned colon or rectal surgery, this study might be for you.
AmiensAges 18 years+ - NCT06865638Recruiting
Testing for colorectal anastomotic leaks after surgery
This trial is testing a new method to check for leaks after colorectal cancer surgery. The goal is to see if it helps prevent complications and improves recovery.
Nanchong, SichuanAges 18–85 - NCT07036588Recruiting
Using a drain tube to prevent leaks after rectal cancer surgery
This trial tests if placing a special drain tube in the anus after rectal cancer surgery can reduce the risk of leakage at the surgical connection. It is for people with rectal cancer who are having surgery to remove the tumor and reconnect the bowel.
Yuzhong, Chongqing MunicipalityAges 18–80 - NCT06493565Recruiting
Early scope check for leak after colorectal surgery
This trial tests whether a routine endoscopic exam shortly after colorectal surgery can catch a leak early, which may prevent complications. If you are 18 or older and had a low colorectal or coloanal anastomosis within 15 cm of the anorectal junction, you may be eligible.
BordeauxAges 18 years+ - NCT07144683Recruiting
Colorectal surgery leak study
This trial is studying how often leaks happen after colorectal surgery that connects two parts of the intestine. It may help doctors better understand and prevent this complication.
Minya, Minya GovernorateAges 18–80 - NCT07035431Recruiting
Endo-SPONGE for Leaks After Colorectal Surgery
This trial tests a treatment called Endo-SPONGE for people who have a leak at the connection site after colorectal surgery. It aims to help the leak heal using a special sponge placed through an endoscope.
Orlando, FloridaAges 18 years+ - NCT07309991Recruiting
Oxygen Levels After Esophageal Cancer Surgery and Healing Complications
This study looks at whether low oxygen levels in the blood after esophageal cancer surgery increases the risk of problems with how the surgery heals. By understanding this connection, doctors may be able to better prevent or treat healing complications.
Guangzhou, GuangdongAges 18–80 - NCT06688383Recruiting
Leak after right colon cancer surgery: a study on outcomes
This study looks at how often a leak happens at the connection site after right colon cancer surgery. It includes both emergency and planned surgeries, and all types of surgical approaches. The goal is to learn more about this complication so doctors can prevent it better.
Orbassano, PiedmontAges 18 years+ - NCT06906289Recruiting
Resuming feeding after small bowel connection surgery
This study looks at the best time to start eating again after small bowel surgery. Patients are placed into groups that start feeding earlier or later, to see which helps recovery better.
Peshawar, KPKAges 15–65 - NCT05606822Recruiting
Vacuum endoscopy for leaks after esophagus stomach surgery
This trial studies an endoscopic vacuum treatment (a suction device placed through an endoscope) to help heal a leak after surgery where food/drink pathways were connected (an anastomosis). If you had an esophago-gastric leak, this treatment may be part of your care plan and is being studied for effectiveness and safety.
AmsterdamAges 18 years+ - NCT05943444Recruiting
Compares two ways to preserve bowel function after rectal surgery
This trial compares two surgical techniques to see which one better preserves anal function after surgery for low rectal cancer. If you may be eligible for anal-preserving surgery, it may help your care team choose the approach that best protects bowel control.
Guangzhou, GuangdongAges 18–75 - NCT06136845Recruiting
Esophageal cancer microbiome and leak after surgery
This study looks at bacteria in esophageal cancer tumors and whether certain bacteria are linked to leaks that can happen after surgery to remove the esophagus. It may help doctors understand how to prevent these leaks in the future.
HaifaAges 18–85 - NCT07125248Recruiting
One vs. Two Drains After Esophageal Cancer Surgery
This study is for people with esophageal cancer who are having open surgery to remove the esophagus. It compares using one chest drain tube versus two to see which leads to a better recovery.
Peshawar, KhyberpukhtunkhwaAges Any age - NCT07132970Recruiting
Leakage rate of sutured bowel connection after right colon removal
This trial is testing how well hand-sewn or partially stitched connections (anastomoses) hold up after right colon removal for cancer. It may help improve surgical techniques for people undergoing this operation.
Göppingen, Baden-WurttembergAges 18 years+ - NCT07209787RecruitingPhase 4
Reinforced vs. standard connection for rectal cancer surgery
This trial tests whether a special reinforcement patch (made from pig tissue) can reduce the risk of leaks when the rectum is reconnected after rectal cancer surgery. It compares the reinforced connection to the standard method.
Beijing, Beijing MunicipalityAges Up to 85 years - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80 - NCT07763379Recruiting
Blood test for early detection of leaks after intestinal surgery
This study checks whether a simple blood test for C-reactive protein (CRP) can help doctors spot a leak early after intestinal surgery. A leak is a serious complication where the repaired area opens up, and early detection may lead to quicker treatment and better recovery.
Sohag, Sohag GovernorateAges 18–70
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Common questions
- Are there clinical trials for anastomotic leak?
- Yes. Clin2 currently lists 23 recruiting anastomotic leak studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anastomotic leak trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anastomotic leak trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.