Clinical trials · Boston, MA
Anxiety clinical trials in Boston
We’re tracking 45 recruiting anxiety studies with a site in or near Boston — including Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT05806112Enrolling by invitation
Improve staff well-being programs for residential care workers
This trial tests whether specific programs can reduce burnout and improve resiliency (coping strength) among staff who work in behavioral health group homes. It may help workers feel better and handle stressful work days.
Boston, MassachusettsAges 18 years+ - NCT07323784RecruitingPhase 2
Study of NTX-1472 for social anxiety disorder
This trial tests an investigational medicine called NTX-1472 to see if it helps people with social anxiety disorder. Participation involves taking the study drug and attending scheduled visits.
Boston, MassachusettsAges 18–65 - NCT05683223Recruiting
Brain and body markers to improve treatment for social anxiety
This study uses brain recordings (EEG and MRI) to understand how treatments help people with social anxiety. It also looks for signals that may predict who is most likely to benefit from treatment.
Boston, MassachusettsAges 18–50 - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT05501834Enrolling by invitation
Anxiety study for kids getting arm pins removed
This study tests if a child life specialist can help reduce anxiety when children have pins removed from their arm after a fracture. If your child is between 3 and 10, had a specific arm fracture treated with pins at Boston Children's Hospital, and speaks English, they may be eligible.
Boston, MassachusettsAges 3–10 - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT06929442Recruiting
Prevention program for young adults with unusual experiences
This study tests a program to help young adults who have had unusual thoughts or experiences (like feeling people are talking about them or that things have hidden meanings) learn ways to cope and feel better. The goal is to prevent these experiences from turning into bigger problems.
Charlestown, MassachusettsAges 18–30 - NCT05649059RecruitingPhase 4
Cannabidiol study for social anxiety symptoms
This trial studies whether cannabidiol (CBD) helps improve social anxiety symptoms. You may be able to join if you are an adult with significant social anxiety and meet medication and health safety requirements.
Cambridge, MassachusettsAges 18–55 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT05232032RecruitingPhase 2
Brain scan and medication study for avoiding versus approaching
This Phase 2 study looks at how a medication affects brain activity and real-life mood or anxiety behaviors. It includes people with major depression or several anxiety disorders and also healthy volunteers, using questionnaires, a smartphone, and brain imaging.
Belmont, MassachusettsAges 18–45 - NCT05457465RecruitingPhase 2
Cannabidiol study for anxiety and depression in bipolar disorder
This Phase 2 study tests whether cannabidiol (CBD) can reduce anxiety and depressive symptoms in people with bipolar disorder. It may help if your mood symptoms are persistent and you’re already on stable bipolar medications.
Belmont, MassachusettsAges 18–65 - NCT05837104RecruitingPhase 2
Magnesium and vitamin B6 for early bipolar depression
This Phase 2 trial tests whether magnesium plus vitamin B6 can reduce depressive symptoms in people who are newly diagnosed with bipolar I disorder. It also checks for safety over a short, 4-week treatment period.
Belmont, MassachusettsAges 18–50 - NCT05665491Recruiting
Study links parent anxiety thinking to child anxiety
This study looks at how a parent’s tendency to interpret situations as more threatening or worrying may affect a child’s anxiety. If you and your child fit the requirements, you may complete questionnaires and phone-based check-ins to help researchers understand what patterns matter.
Belmont, MassachusettsAges 7 years+ - NCT03723928Recruiting
Blood test–guided monitoring for metastatic breast cancer treatment
This study checks whether specific blood “tumor marker” levels can help monitor how hormone receptor–positive, HER2-negative metastatic breast cancer responds to first-line therapy. It uses regular blood tests (and sometimes scans) to see if this marker-based monitoring is useful and reliable.
Winchester, MassachusettsAges 18 years+ - NCT07036757Recruiting
Healthy meal kits for better health
This study provides free healthy meal kits to adults with overweight and health concerns to see if they can improve blood sugar, blood pressure, and weight. It is for people 40 and older with low income who live in the Greater Lowell area.
Lowell, MassachusettsAges 40 years+ - NCT06790641Recruiting
Supporting mental health during and after pregnancy
This study aims to improve mental health care for people during and after pregnancy. It involves interviews or focus groups with healthcare providers, peer mentors, and patients to understand how to make support services more helpful and accessible.
Shrewsbury, MassachusettsAges 18–70 - NCT06898593Recruiting
Including patient goals in collaborative care
This trial looks at ways to better include your personal goals and concerns in your care if you're already in the Collaborative Care Model at Dartmouth Health. It aims to make your treatment more focused on what matters to you.
Nashua, New HampshireAges 18–100 - NCT06934525Recruiting
Team therapy for childhood anxiety and OCD
This study tests a team-based therapy approach for children and teens with anxiety or OCD. It helps families get treatment in community mental health centers, not just in specialized clinics.
East Providence, Rhode IslandAges 5–18 - NCT07591922Recruiting
Music therapy during heart valve replacement surgery
This study tests whether listening to music during a minimally sedated heart valve replacement procedure (TAVR) helps reduce anxiety and improve the patient experience. You would wear headphones and listen to calming music while awake during the procedure.
Providence, Rhode IslandAges 18 years+ - NCT07594743Recruiting
Digital app to prevent depression in new fathers
This study tests a smartphone app designed to help fathers manage stress and mood after their baby is born. Researchers want to see if fathers find the app helpful and easy to use during this major life change.
Providence, Rhode IslandAges 18 years+ - NCT07379853Enrolling by invitation
Online training for therapists in exposure therapy
This trial tests an online training program to help therapists learn exposure therapy for anxiety. It may improve your skills in treating anxiety disorders.
Riverside, Rhode IslandAges 21–99
Hear when a new Anxiety trial opens near Boston, MA
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Anxiety trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting anxiety studies listed above.
- McLean Hospital · 4 studies
- Massachusetts General Hospital · 3 studies
- Boston University · 2 studies
- Bradley Hospital · 2 studies
- Boston Children's Hospital
- Clinical Study Site
- Dartmouth Hitchcock Nashua Family Practice
- Dartmouth Hitchcock Nashua General Internal Medicine
What taking part in a anxiety study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting anxiety studies in Massachusetts.
Common questions
- Are there anxiety clinical trials near Boston?
- Yes. We're currently tracking 45 recruiting anxiety studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a anxiety study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New anxiety studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.