Clinical trials · Massachusetts
Anxiety clinical trials in Massachusetts
We’re tracking 42 recruiting anxiety studies with a site in Massachusetts — including Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05683223Recruiting
Brain and body markers to improve treatment for social anxiety
This study uses brain recordings (EEG and MRI) to understand how treatments help people with social anxiety. It also looks for signals that may predict who is most likely to benefit from treatment.
Boston, MassachusettsAges 18–50 - NCT07458698Recruiting
A digital program to prevent anxiety during pregnancy
This study tests a mobile app called Reaching Calm that may help prevent anxiety disorders in pregnant people. It is for those who are already receiving prenatal care and have mild to moderate anxiety symptoms.
Leominster, MassachusettsAges 18 years+ - NCT07439042RecruitingPhase 4
Buspirone for anxiety in children with autism
This trial tests whether buspirone, a medication that helps with anxiety, can reduce anxiety in children and teens with autism. It is a 12-week study where participants receive buspirone or a placebo (a pill with no medicine) to see if it improves anxiety symptoms.
Lexington, MassachusettsAges 7–17 - NCT07323784RecruitingPhase 2
Study of NTX-1472 for social anxiety disorder
This trial tests an investigational medicine called NTX-1472 to see if it helps people with social anxiety disorder. Participation involves taking the study drug and attending scheduled visits.
Boston, MassachusettsAges 18–65 - NCT07305740Recruiting
Online program for anxiety in cancer survivors
This study tests an online program to help cancer survivors manage anxiety. You may qualify if you finished cancer treatment at least 4 months ago and still feel significant anxiety.
Boston, MassachusettsAges 18 years+ - NCT07153250Recruiting
Online parent training for young child anxiety
This trial tests an online program that teaches parents how to help their young child (ages 2 to 7) manage anxiety. You would complete the program at home, and researchers want to see if it reduces your child's anxiety symptoms.
Boston, MassachusettsAges 18 years+ - NCT06846320RecruitingPhase 2
Study of ABBV-932 for generalized anxiety disorder
This trial tests an oral medicine called ABBV-932 when added to current antidepressant therapy for people with generalized anxiety disorder (GAD) who still have symptoms. It aims to see if the combination can improve anxiety and reduce side effects.
Springfield, MassachusettsAges 18–65 - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Boston, MassachusettsAges 18–65 - NCT05665491Recruiting
Study links parent anxiety thinking to child anxiety
This study looks at how a parent’s tendency to interpret situations as more threatening or worrying may affect a child’s anxiety. If you and your child fit the requirements, you may complete questionnaires and phone-based check-ins to help researchers understand what patterns matter.
Belmont, MassachusettsAges 7 years+ - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT05501834Enrolling by invitation
Anxiety study for kids getting arm pins removed
This study tests if a child life specialist can help reduce anxiety when children have pins removed from their arm after a fracture. If your child is between 3 and 10, had a specific arm fracture treated with pins at Boston Children's Hospital, and speaks English, they may be eligible.
Boston, MassachusettsAges 3–10 - NCT04912531Recruiting
Virtual reality and smell tools to ease surgery pain
This trial tests whether a combination of virtual reality and guided smells can reduce pain and anxiety around major heart and chest surgeries. If you’re scheduled for one of the listed operations, the study may help make recovery feel more comfortable by using sensory-based distraction.
Boston, MassachusettsAges 18 years+ - NCT04557891Recruiting
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Boston, MassachusettsAges 18–65 - NCT06654414Recruiting
Smoking cessation support for transgender and gender-diverse adults
This study tests a skills-based program to help transgender and gender-diverse adults quit smoking or vaping. The program focuses on managing stress related to identity and health, and may be more supportive than standard quit programs.
Boston, MassachusettsAges 18 years+ - NCT07217561Recruiting
Doula support program to improve mental health before and after birth
This trial tests whether extra training and resources for doulas can help pregnant people and new parents feel better emotionally. Doulas who join will learn new ways to support clients, and participants will get care from a trained doula.
Boston, MassachusettsAges Any age - NCT07143357Recruiting
Recovering together: support for cardiac arrest survivors and caregivers
This study tests a mind-body program to help cardiac arrest survivors and their caregivers cope with emotional distress after the event. It combines in-person and video sessions to improve well-being together.
Boston, MassachusettsAges 18 years+ - NCT07091032Recruiting
Building connections for better health
This study tests if helping people address obesity, cancer screenings, or mental health struggles can improve their overall health. You may qualify if you have obesity, are behind on colon or cervical cancer screening, or have depression or anxiety.
Boston, MassachusettsAges 18–75 - NCT07048574Recruiting
Mood and behavior in children with cystic fibrosis
This study looks at mood and behavior in children with cystic fibrosis (CF) under 12. By following children over time, researchers hope to better understand and help with depression, anxiety, and behavior challenges that may come up.
Boston, MassachusettsAges 1.5 years–11 years - NCT07036757Recruiting
Healthy meal kits for better health
This study provides free healthy meal kits to adults with overweight and health concerns to see if they can improve blood sugar, blood pressure, and weight. It is for people 40 and older with low income who live in the Greater Lowell area.
Lowell, MassachusettsAges 40 years+ - NCT06969105Recruiting
Music for comfort during labor and delivery
This study tests whether listening to music during labor can help reduce pain and anxiety. Researchers will compare outcomes for laboring women who listen to music versus those who do not.
Boston, MassachusettsAges 18 years+ - NCT06929442Recruiting
Prevention program for young adults with unusual experiences
This study tests a program to help young adults who have had unusual thoughts or experiences (like feeling people are talking about them or that things have hidden meanings) learn ways to cope and feel better. The goal is to prevent these experiences from turning into bigger problems.
Charlestown, MassachusettsAges 18–30 - NCT06812247Recruiting
Therapy dog visits for hospitalized trauma patients
This study looks at whether visits from therapy dogs can help people who are in the hospital after a traumatic injury feel better. You must be able to talk to the research team and not be afraid of dogs.
Boston, MassachusettsAges 18 years+ - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06790641Recruiting
Supporting mental health during and after pregnancy
This study aims to improve mental health care for people during and after pregnancy. It involves interviews or focus groups with healthcare providers, peer mentors, and patients to understand how to make support services more helpful and accessible.
Shrewsbury, MassachusettsAges 18–70
Anxiety trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting anxiety studies listed above.
- Massachusetts General Hospital · 7 studies
- Beth Israel Deaconess Medical Center
- Boston Children's Hospital
- Boston Medical Center, Trauma Inpatient Service
- Boston University
- Boston University - Charles River Campus
- Brigham and Women's Hospital
- Center for Anxiety and Related Disorders at Boston University
What taking part in a anxiety study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Anxiety trials in other states
Common questions
- Are there anxiety clinical trials in Massachusetts?
- Yes. We're currently tracking 42 recruiting anxiety studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a anxiety study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New anxiety studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.