Clinical trials
Bipolar and Related Disorders clinical trials
Below are recruiting bipolar and related disorders clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06811311Recruiting
Hypnotherapy and Brain Activity in Generalized Anxiety Disorder
This study uses EEG (a brain wave test) to see how Ericksonian hypnotherapy, a gentle type of hypnosis, affects brain activity and anxiety symptoms in people with Generalized Anxiety Disorder (GAD) who are not currently in treatment or taking medication for anxiety.
IstanbulAges 18–65 - NCT05943171Recruiting
App-based CBT for substance dependence and relationship aggression
This study tests an app-guided version of CBT (a structured talk-therapy approach) against standard CBT to help people with substance dependence and recent verbal aggression in an intimate relationship. You may be screened to see if you fit both the substance use and relationship aggression parts of the trial.
Rochester, New YorkAges 18–65 - NCT07573839Recruiting
Predicting bipolar disorder relapse using voice and video analysis
This study uses artificial intelligence to analyze speech patterns and facial expressions from people with bipolar disorder to predict who might have a relapse. If successful, it could help doctors identify warning signs earlier and prevent episodes before they happen.
ShanghaiAges 18–64 - NCT04899687RecruitingPhase 2
Dextromethorphan for OCD and related anxiety conditions
This trial studies dextromethorphan, a medicine sometimes used for cough, to see if it can reduce symptoms in OCD and similar conditions. It may help people whose intrusive thoughts or related worries are still challenging despite current care.
Stanford, CaliforniaAges 18–65 - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT05886582RecruitingPhase 2
Rotigotine patch added to therapy for cocaine use
This Phase 2 study tests whether a rotigotine skin patch, used alongside behavioral therapy, can help people reduce cocaine use. It also looks at changes in brain activity while you do study tasks.
Richmond, VirginiaAges 25–70 - NCT07053098Recruiting
Boosting Alcohol Use Disorder Meds in Psychiatric Care
This study aims to help doctors and staff at three psychiatric clinics better prescribe medications for alcohol use disorder to patients with serious mental illness. It looks at whether extra support and guidance can improve treatment.
Baltimore, MarylandAges 18–90 - NCT06629064Recruiting
Memory training for PTSD symptoms
This study tests a computer-based memory training program for people with PTSD. It aims to see if this training can help reduce PTSD symptoms by improving how your brain processes memories. The study involves 8 remote sessions over 4 weeks and two MRI scans to look at brain changes.
San Diego, CaliforniaAges 18–65 - NCT06665984Recruiting
Greater Houston pediatric bipolar registry study
This study is creating a registry to learn more about bipolar disorder in children and teens. It includes youth who have bipolar disorder and those who have a parent with bipolar disorder, as well as healthy youth for comparison.
Houston, TexasAges 6–17 - NCT04727489Recruiting
Study genes in autism and related conditions using blood samples
This study looks for genetic reasons for autism by collecting blood samples from people with autism, people without autism, and their relatives. The results may help researchers better understand causes and risk factors, even if you only participate through testing a sample.
Grenoble, GrenobleAges 2–70 - NCT06454903Recruiting
Smartphone app to help veterans with opioid use disorder treatment
This study tests a smartphone app designed to support veterans who are receiving medication treatment for opioid use disorder. It aims to see if the app helps improve treatment outcomes.
West Haven, ConnecticutAges 18 years+ - NCT06636227RecruitingPhase 1
Diclofenac dose study for alcohol use disorder
This study tests whether different doses of diclofenac, an anti-inflammatory drug, can help people reduce heavy drinking. It looks at how the drug affects drinking patterns and overall health.
Catonsville, MarylandAges 21–65 - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT07185815RecruitingPhase 1/Phase 2
Study of a long-acting cariprazine shot for mood and schizophrenia
This trial tests a monthly injection of cariprazine (a medication for mental health conditions) in people who could benefit from it. It aims to see if the shot is safe, tolerable, and effective compared to taking pills every day.
AhmedabadAges 18–64 - NCT07214207RecruitingPhase 2
Testing a sleep medicine for alcohol use disorder and stress-related drinking
This trial tests whether a medicine called suvorexant, which is used for sleep, can help people with alcohol use disorder drink less, especially when stressed. You would receive the medicine or a placebo, and researchers will track your drinking and stress levels over several weeks.
Columbus, OhioAges 18–65 - NCT06001749RecruitingPhase 2
Psilocybin for cancer pain study
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Boston, MassachusettsAges 18 years+ - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70 - NCT06188754Recruiting
Healthy lifestyle program for bipolar disorder and sleep issues
This study tests a healthy lifestyle program (including diet changes) for people with bipolar disorder who have sleep problems. It aims to improve sleep and overall well-being by teaching new habits.
Berkeley, CaliforniaAges 18–65 - NCT06363981Recruiting
Brain stimulation for depression, sleep and memory problems
This study tests a non-invasive brain stimulation treatment (called rTMS) to help with depression, sleep problems, and memory or concentration issues. It's designed for people with moderate to severe depression who also have trouble sleeping and thinking clearly.
KrakowAges 18–65 - NCT06494319Recruiting
PTSD treatment app for veterans with combat trauma
This study tests a virtual training program and mobile app to help veterans manage PTSD from combat. It aims to reduce symptoms and improve daily life.
Houston, TexasAges 18–79 - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+ - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06247839RecruitingPhase 3
Psilocybin for depression: changing self-focus
This trial tests whether a single dose of psilocybin can help people with treatment-resistant depression by changing how they focus on themselves. It aims to understand how psilocybin affects brain activity and self-related thinking.
Charlestown, MassachusettsAges 18–55
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Common questions
- Are there clinical trials for bipolar and related disorders?
- Yes. Clin2 currently lists 58 recruiting bipolar and related disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar and related disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar and related disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.